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Tbio
FKBP9
Peptidyl-prolyl cis-trans isomerase FKBP9

Protein Summary
Description
PPIases accelerate the folding of proteins during protein synthesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000242209
  • ENSP00000242209
  • ENSG00000122642
  • ENST00000490776
  • ENSP00000441317
  • ENST00000538336
  • ENSP00000439250

Symbol
  • FKBP60
  • FKBP63
  • FKBP60
  • FKBP63
  • PPIase
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.97
histone modification site profile
0.75
protein domain
0.73
kinase perturbation
0.71
transcription factor perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.38   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 73   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.38   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (59)
P0CG13
Tbio
Novelty:  0.15007488
p_int:  0.999999891
p_ni:  1.08e-7
p_wrong:  2e-9
Score:  0.189
Data Source:  BioPlex,STRINGDB
TCF20
Tbio
Family:  Epigenetic
Novelty:  0.00089239
p_int:  0.99999559
p_ni:  0.00000441
Score:  0.402
Data Source:  BioPlex,STRINGDB
RAVER1
Tbio
Novelty:  0.08620158
p_int:  0.999988029
p_ni:  0.000011971
Score:  0.192
Data Source:  BioPlex,STRINGDB
CBY1
Tbio
Novelty:  0.0205109
p_int:  0.999928854
p_ni:  0.00004747
p_wrong:  0.000023676
Score:  0.243
Data Source:  BioPlex,STRINGDB
TCF3
Tbio
Family:  TF
Novelty:  0.00112675
p_int:  0.99962585
p_ni:  0.00037415
Score:  0.173
Data Source:  BioPlex,STRINGDB
COL4A6
Tbio
Novelty:  0.02524039
p_int:  0.999581134
p_ni:  0.000415945
p_wrong:  0.000002921
Score:  0.279
Data Source:  BioPlex,STRINGDB
COL2A1
Tbio
Novelty:  0.0011102
p_int:  0.998671448
p_ni:  0.001328548
p_wrong:  4e-9
Score:  0.202
Data Source:  BioPlex,STRINGDB
PTPRS
Tchem
Family:  Enzyme
Novelty:  0.00587115
p_int:  0.996109287
p_ni:  0.003890713
Score:  0.164
Data Source:  BioPlex,STRINGDB
ADAMTS12
Tbio
Family:  Enzyme
Novelty:  0.03184816
p_int:  0.991848163
p_ni:  0.008151837
Score:  0.541
Data Source:  BioPlex,STRINGDB
COL4A2
Tbio
Novelty:  0.00782053
p_int:  0.972187907
p_ni:  0.027812093
Score:  0.303
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Association of TriC/CCT with target proteins during biosynthesis (R-HSA-390471)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Association of TriC/CCT with target proteins during biosynthesis
Reactome
Chaperonin-mediated protein folding
Reactome
Metabolism of proteins
Reactome
Protein folding
Name
Explore in Pharos
Explore in Source
Association of TriC/CCT with target proteins during biosynthesis
Chaperonin-mediated protein folding
Metabolism of proteins
Protein folding
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (19)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
5
7
99
reticulocyte count
2
2
2
85
reticulocyte measurement
2
2
2
81.6
glomerular filtration rate
4
4
4
78.5
mean reticulocyte volume
1
2
2
71.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
7
99
reticulocyte count
2
85
reticulocyte measurement
2
81.6
glomerular filtration rate
4
78.5
mean reticulocyte volume
2
71.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
FK506 binding protein 9
VGNC:4359
463339
Macaque
FK506 binding protein 9
708827
Mouse
MGI:1350921
27055
Rat
RGD:1549757
297123
Dog
FK506 binding protein 9
VGNC:40895
475276
Species
Name
OMA
EggNOG
Inparanoid
Chimp
FK506 binding protein 9
Macaque
FK506 binding protein 9
Mouse
Rat
Dog
FK506 binding protein 9
Publication Statistics
PubMed Score 6.38
PubMed score by year
PubTator Score 6.88
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title