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Tbio
FGFR1OP2
FGFR1 oncogene partner 2

Protein Summary
Description
May be involved in wound healing pathway.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000229395
  • ENSP00000229395
  • ENSG00000111790
  • ENST00000327214
  • ENSP00000323763
  • ENST00000546072
  • ENSP00000437556

Symbol
  • WIT3.0
  • HSPC123-like
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
cell type or tissue
0.86
histone modification site profile
0.86
virus perturbation
0.76
transcription factor binding site profile
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.95   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 198   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.95   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 198   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (91)
TRAF3IP3
Tbio
Novelty:  0.12180834
p_int:  1
Score:  0.86
Data Source:  BioPlex,STRINGDB
RGPD8
Tdark
Novelty:  0.12397737
p_int:  0.999999379
p_ni:  6.21e-7
Data Source:  BioPlex
TNFRSF1A
Tchem
Novelty:  0.00037847
p_int:  0.999998959
p_ni:  0.000001041
Data Source:  BioPlex
SLMAP
Tbio
Novelty:  0.03974856
p_int:  0.999991223
p_ni:  0.000008777
Score:  0.883
Data Source:  BioPlex,STRINGDB
RGPD5
Tbio
Novelty:  0.13776125
p_int:  0.99998618
p_ni:  0.00001382
Data Source:  BioPlex
CCHCR1
Tbio
Novelty:  0.03045656
p_int:  0.999982537
p_ni:  0.000017463
Data Source:  BioPlex
PPP2CB
Tbio
Family:  Enzyme
Novelty:  0.0483178
p_int:  0.999973816
p_ni:  0.000026155
p_wrong:  2.9e-8
Score:  0.454
Data Source:  BioPlex,STRINGDB
PPP2R1A
Tbio
Family:  Enzyme
Novelty:  0.01134139
p_int:  0.999944796
p_ni:  0.000055128
p_wrong:  7.6e-8
Score:  0.414
Data Source:  BioPlex,STRINGDB
RABEP2
Tbio
Family:  Enzyme
Novelty:  0.18180682
p_int:  0.999936729
p_ni:  0.000063271
Data Source:  BioPlex
PLP1
Tbio
Novelty:  0.00129083
p_int:  0.999905309
p_ni:  0.000094666
p_wrong:  2.5e-8
Score:  0.196
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (6)
Disease (R-HSA-1643685)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Disease
Reactome
Diseases of signal transduction
Reactome
FGFR1 mutant receptor activation
Reactome
Signaling by FGFR in disease
Reactome
Signaling by FGFR1 in disease
Name
Explore in Pharos
Explore in Source
Disease
Diseases of signal transduction
FGFR1 mutant receptor activation
Signaling by FGFR in disease
Signaling by FGFR1 in disease
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
basophil percentage of leukocytes
1
1
1
62.1
self reported educational attainment
1
1
1
57.8
basophil count
2
1
2
52
1
1
1
49.5
mean corpuscular volume
1
1
1
26.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
basophil percentage of leukocytes
1
62.1
self reported educational attainment
1
57.8
basophil count
2
52
1
49.5
mean corpuscular volume
1
26.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
FGFR1 oncogene partner 2
VGNC:8410
738902
Macaque
FGFR1 oncogene partner 2
708905
Mouse
MGI:1914779
67529
Rat
RGD:1303233
362463
Dog
FGFR1 oncogene partner 2
VGNC:40858
486626
Species
Name
OMA
EggNOG
Inparanoid
Chimp
FGFR1 oncogene partner 2
Macaque
FGFR1 oncogene partner 2
Mouse
Rat
Dog
FGFR1 oncogene partner 2
Publication Statistics
PubMed Score 8.95
PubMed score by year
PubTator Score 10.99
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title