FGB
Fibrinogen beta chain
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.97 | ||
gene perturbation | 0.97 | ||
cell type or tissue | 0.76 | ||
protein domain | 0.73 | ||
kinase perturbation | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Common Pathway of Fibrin Clot Formation | ||||
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Disease | ||||
Reactome | Diseases of signal transduction | ||||
Reactome | Extracellular matrix organization | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Common Pathway of Fibrin Clot Formation | ||||
Cytokine Signaling in Immune system | ||||
Disease | ||||
Diseases of signal transduction | ||||
Extracellular matrix organization | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
fibrinogen measurement | 8 | 14 | 14 | 12.9 | 99.8 | ||||
7 | 5 | 2 | 1.2 | 98.2 | |||||
low density lipoprotein cholesterol measurement | 3 | 3 | 3 | 89.2 | |||||
prothrombin time measurement | 1 | 1 | 1 | 72.9 | |||||
total cholesterol measurement | 3 | 2 | 3 | 70.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
fibrinogen measurement | 14 | 12.9 | 99.8 | ||||
2 | 1.2 | 98.2 | |||||
low density lipoprotein cholesterol measurement | 3 | 89.2 | |||||
prothrombin time measurement | 1 | 72.9 | |||||
total cholesterol measurement | 3 | 70.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | fibrinogen beta chain | VGNC:606 | 461558 | |||||
Macaque | fibrinogen beta chain | 698487 | ||||||
Mouse | MGI:99501 | 110135 | ||||||
Rat | RGD:2604 | 24366 | ||||||
Dog | fibrinogen beta chain | VGNC:54207 | 475472 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | fibrinogen beta chain | |||||
Macaque | fibrinogen beta chain | |||||
Mouse | ||||||
Rat | ||||||
Dog | fibrinogen beta chain | |||||
PMID | Year | Title |
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