FCAR
Immunoglobulin alpha Fc receptor
Protein Summary
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- ENST00000345937
- ENSP00000338257
- ENSG00000186431
- ENST00000353758
- ENSP00000338058
- ENST00000355524
- ENSP00000347714
- ENST00000359272
- ENSP00000352218
- ENST00000391723
- ENSP00000375603
- ENST00000391724
- ENSP00000375604
- ENST00000391725
- ENSP00000375605
- ENST00000391726
- ENSP00000375606
- ENST00000469767
- ENSP00000473814
- ENST00000488066
- ENSP00000474512
- ENST00000610340
- ENSP00000477610
- ENSG00000275136
- ENST00000610397
- ENSP00000480965
- ENSG00000275269
- ENST00000610786
- ENSP00000483121
- ENSG00000276858
- ENST00000611018
- ENSP00000484483
- ENSG00000275970
- ENST00000611130
- ENSP00000484917
- ENSG00000273738
- ENST00000611871
- ENSP00000482976
- ENST00000611943
- ENSP00000482273
- ENSG00000275564
- ENST00000612150
- ENSP00000478233
- ENST00000612159
- ENSP00000484662
- ENSG00000276985
- ENST00000612505
- ENSP00000479792
- ENST00000612803
- ENSP00000478454
- ENST00000612815
- ENSP00000483503
- ENST00000612918
- ENSP00000482056
- ENSG00000274580
- ENST00000613199
- ENSP00000478465
- ENST00000613201
- ENSP00000482108
- ENST00000613298
- ENSP00000482451
- ENST00000613318
- ENSP00000481560
- ENST00000613663
- ENSP00000483437
- ENST00000613685
- ENSP00000481230
- ENST00000614226
- ENSP00000483099
- ENST00000614298
- ENSP00000483472
- ENST00000614433
- ENSP00000480748
- ENST00000614689
- ENSP00000480013
- ENST00000614893
- ENSP00000477966
- ENST00000614917
- ENSP00000479831
- ENST00000614954
- ENSP00000479924
- ENST00000615040
- ENSP00000477656
- ENST00000615110
- ENSP00000484276
- ENST00000615361
- ENSP00000482741
- ENST00000615703
- ENSP00000484868
- ENST00000615719
- ENSP00000482518
- ENST00000615800
- ENSP00000483841
- ENST00000615829
- ENSP00000482623
- ENST00000615937
- ENSP00000478075
- ENST00000616340
- ENSP00000481676
- ENST00000616878
- ENSP00000480970
- ENST00000616969
- ENSP00000479039
- ENST00000617025
- ENSP00000481129
- ENST00000617609
- ENSP00000481394
- ENST00000617696
- ENSP00000482670
- ENST00000617762
- ENSP00000484136
- ENST00000617766
- ENSP00000479230
- ENST00000617778
- ENSP00000480498
- ENST00000617964
- ENSP00000484141
- ENST00000618271
- ENSP00000484741
- ENST00000618287
- ENSP00000481668
- ENST00000618328
- ENSP00000480496
- ENST00000618658
- ENSP00000479688
- ENST00000618805
- ENSP00000481985
- ENST00000618985
- ENSP00000480323
- ENST00000619073
- ENSP00000479360
- ENST00000619155
- ENSP00000480461
- ENST00000619385
- ENSP00000482334
- ENST00000619414
- ENSP00000478163
- ENST00000619822
- ENSP00000483250
- ENST00000620162
- ENSP00000483258
- ENST00000620179
- ENSP00000478315
- ENSG00000278415
- ENST00000620270
- ENSP00000482022
- ENST00000620397
- ENSP00000477584
- ENST00000620801
- ENSP00000481195
- ENST00000620822
- ENSP00000483327
- ENST00000620873
- ENSP00000479099
- ENST00000621004
- ENSP00000484816
- ENST00000621009
- ENSP00000482025
- ENST00000621289
- ENSP00000481366
- ENST00000621417
- ENSP00000478634
- ENST00000621684
- ENSP00000479239
- ENST00000621702
- ENSP00000482807
- ENST00000621755
- ENSP00000484906
- ENST00000621882
- ENSP00000484272
- ENST00000622157
- ENSP00000481502
- ENST00000622470
- ENSP00000477673
- ENST00000622491
- ENSP00000477643
- ENST00000622543
- ENSP00000483402
- ENST00000622646
- ENSP00000480406
- ENST00000622737
- ENSP00000479738
- ENST00000622777
- ENSP00000481345
- ENST00000622883
- ENSP00000479880
- ENST00000622904
- ENSP00000480444
- ENST00000638206
- ENSP00000492749
- ENSG00000284061
- ENST00000638212
- ENSP00000492230
- ENST00000638238
- ENSP00000492629
- ENSG00000283750
- ENST00000638242
- ENSP00000492364
- ENST00000638244
- ENSP00000492699
- ENSG00000283953
- ENST00000638285
- ENSP00000491595
- ENST00000638290
- ENSP00000492003
- ENST00000638453
- ENSP00000491493
- ENST00000638527
- ENSP00000491362
- ENSG00000284245
- ENST00000638553
- ENSP00000491372
- ENSG00000284004
- ENST00000638625
- ENSP00000492755
- ENST00000638882
- ENSP00000492226
- ENST00000638900
- ENSP00000491778
- ENST00000638906
- ENSP00000492268
- ENST00000638945
- ENSP00000492228
- ENST00000638966
- ENSP00000491307
- ENST00000638995
- ENSP00000491741
- ENST00000639014
- ENSP00000491039
- ENST00000639163
- ENSP00000491556
- ENST00000639178
- ENSP00000492137
- ENST00000639193
- ENSP00000491447
- ENST00000639223
- ENSP00000492274
- ENST00000639337
- ENSP00000491914
- ENST00000639392
- ENSP00000492068
- ENST00000639402
- ENSP00000492442
- ENST00000639426
- ENSP00000492415
- ENST00000639428
- ENSP00000491642
- ENST00000639455
- ENSP00000491849
- ENST00000639575
- ENSP00000492321
- ENST00000639763
- ENSP00000491420
- ENST00000640025
- ENSP00000492529
- ENST00000640032
- ENSP00000492077
- ENST00000640047
- ENSP00000490997
- ENST00000640063
- ENSP00000491889
- ENST00000640070
- ENSP00000491192
- ENST00000640239
- ENSP00000492762
- ENST00000640405
- ENSP00000491490
- ENST00000640415
- ENSP00000491274
- ENST00000640430
- ENSP00000492494
- ENST00000640462
- ENSP00000491298
- ENST00000640562
- ENSP00000492074
- ENST00000640582
- ENSP00000492447
- ENST00000640584
- ENSP00000491818
- ENST00000640618
- ENSP00000491815
- ENST00000640687
- ENSP00000492597
- ENST00000640761
- ENSP00000492411
- ENST00000640811
- ENSP00000492678
- ENST00000640878
- ENSP00000492686
- ENST00000640908
- ENSP00000492162
- ENST00000640918
- ENSP00000491746
- CD89
- CD89
- FcalphaRI
- CTB-61M7.2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
tissue sample | 0.68 | ||
microRNA | 0.6 | ||
cell type or tissue | 0.58 | ||
biological term | 0.57 | ||
cell line | 0.54 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 297.76 (req: < 5)
Gene RIFs: 39 (req: <= 3)
Antibodies: 593 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 297.76 (req: >= 5)
Gene RIFs: 39 (req: > 3)
Antibodies: 593 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 15
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0