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Tdark
FAXC
Failed axon connections homolog

Protein Summary
Description
May play a role in axonal development.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000389677
  • ENSP00000374328
  • ENSG00000146267
  • ENST00000538471
  • ENSP00000445267

Symbol
  • C6orf168
  • C6orf168
  • dJ273F20
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.79
histone modification site profile
0.7
microRNA
0.69
phenotype
0.55
kinase perturbation
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.78   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 45   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.78   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 45   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (22)
SOBP
Tbio
Novelty:  0.11592489
Score:  0.706
Data Source:  STRINGDB
MMS22L
Tbio
Novelty:  0.22570578
Score:  0.693
Data Source:  STRINGDB
ENTHD1
Tdark
Novelty:  5.29427978
Score:  0.595
Data Source:  STRINGDB
CGREF1
Tbio
Novelty:  0.21713964
Score:  0.498
Data Source:  STRINGDB
SLITRK2
Tbio
Novelty:  0.18828177
Score:  0.495
Data Source:  STRINGDB
ANO5
Tbio
Novelty:  0.01237979
Score:  0.49
Data Source:  STRINGDB
GJA9
Tbio
Novelty:  0.17967582
Score:  0.476
Data Source:  STRINGDB
FBXL4
Tbio
Novelty:  0.04286856
Score:  0.471
Data Source:  STRINGDB
AMD1
Tchem
Family:  Enzyme
Novelty:  0.00231813
Score:  0.459
Data Source:  STRINGDB
EGFL8
Tbio
Novelty:  0.01309625
Score:  0.457
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
failed axon connections homolog
VGNC:2828
472078
Macaque
failed axon connections homolog
693945
Mouse
MGI:1923382
76132
Rat
RGD:1562449
366333
Dog
failed axon connections homolog
475003
Species
Name
OMA
EggNOG
Inparanoid
Chimp
failed axon connections homolog
Macaque
failed axon connections homolog
Mouse
Rat
Dog
failed axon connections homolog
Publication Statistics
PubMed Score 1.78
PubMed score by year
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Related Publications
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PMID
Year
Title