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Tdark
FANCD2OS
FANCD2 opposite strand protein

Protein Summary
Description
This gene encodes a conserved protein of unknown function. [provided by RefSeq, Jan 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000450660
  • ENSP00000429608
  • ENSG00000163705
  • ENST00000524279
  • ENSP00000429663

Symbol
  • C3orf24
  • C3orf24
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.8
gene perturbation
0.78
PubMedID
0.78
cell line
0.55
cell type or tissue
0.52


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.9   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.9   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (48)
DYRK1B
Tchem
Family:  Kinase
Novelty:  0.01960932
p_int:  0.999999895
p_ni:  1.01e-7
p_wrong:  4e-9
Data Source:  BioPlex
AUTS2
Tbio
Novelty:  0.01782909
p_int:  0.999999472
p_ni:  5.27e-7
p_wrong:  1e-9
Data Source:  BioPlex
CNOT6
Tbio
Novelty:  0.03605299
p_int:  0.99999928
p_ni:  7.2e-7
Data Source:  BioPlex
FBRSL1
Tdark
Novelty:  0.53733998
p_int:  0.999998387
p_ni:  0.00000161
p_wrong:  3e-9
Data Source:  BioPlex
CNOT6L
Tbio
Novelty:  0.06038336
p_int:  0.999998171
p_ni:  0.000001829
Data Source:  BioPlex
TNKS1BP1
Tbio
Family:  Enzyme
Novelty:  0.21682007
p_int:  0.999993465
p_ni:  0.000006535
Data Source:  BioPlex
TROAP
Tbio
Novelty:  0.06268103
p_int:  0.999991623
p_ni:  0.000008364
p_wrong:  1.4e-8
Data Source:  BioPlex
CNOT2
Tbio
Novelty:  0.01886737
p_int:  0.999987524
p_ni:  0.000012476
Data Source:  BioPlex
CNOT11
Tbio
Novelty:  0.01687183
p_int:  0.999981738
p_ni:  0.000018002
p_wrong:  2.61e-7
Data Source:  BioPlex
DYRK1A
Tchem
Family:  Kinase
Novelty:  0.00226963
p_int:  0.999960574
p_ni:  0.000039425
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
4
3
5
82.9
eosinophil percentage of leukocytes
2
3
3
74.1
body weight
1
1
1
63.2
BMI-adjusted hip circumference
2
2
3
48.7
eosinophil percentage of granulocytes
1
1
1
30.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
5
82.9
eosinophil percentage of leukocytes
3
74.1
body weight
1
63.2
BMI-adjusted hip circumference
3
48.7
eosinophil percentage of granulocytes
1
30.9
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
FANCD2 opposite strand
VGNC:14237
740619
Macaque
FANCD2 opposite strand
715980
Mouse
MGI:1918229
70979
Rat
RGD:1565997
500294
Dog
FANCD2 opposite strand [Source:HGNC Symbol;Acc:HGNC:28623]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
FANCD2 opposite strand
Macaque
FANCD2 opposite strand
Mouse
Rat
Dog
FANCD2 opposite strand [Source:HGNC Symbol;Acc:HGNC:28623]
Publication Statistics
PubMed Score 0.90
PubMed score by year
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Related Publications
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PMID
Year
Title