Tdark FAM90A1 Protein FAM90A1

Protein Summary

Description

FAM90A1 belongs to subfamily I of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]).[supplied by OMIM, Oct 2009]

Uniprot Accession IDs

• Q86YD7
• D3DUU9
• Q9NVZ6

Gene Name

• FAM90A1

Ensembl ID

• ENST00000307435
• ENSP00000307798
• ENSG00000171847
• ENST00000538603
• ENSP00000445418

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.9
tissue sample	0.66
cell line	0.59
cell type or tissue	0.59
tissue	0.55

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.82   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 31   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.82   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 31   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Protein Sequence and Structure

Residue Counts

Protein Sequence

Find Targets by Sequence

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Expression Data (0 Tissues)

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No expression data found

Related Tools

Target Illumination GWAS Analytics (TIGA)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

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GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

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GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

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ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

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Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (27)

Explore Interacting Targets

1 – 10 of 27

• See Interactions on String-DB

BRD3

Tchem

Family:  Epigenetic

Novelty:  0.00335409

p_int:  1

Score:  0.811

Data Source:  BioPlex,STRINGDB

FAM90A26

Tdark

p_int:  1

Score:  0.4

Data Source:  BioPlex,STRINGDB

BRD4

Tchem

Family:  Epigenetic

Novelty:  0.0013933

p_int:  1

Score:  0.201

Data Source:  BioPlex,STRINGDB

FAM90A5P

Tdark

p_int:  0.999999999

p_wrong:  1e-9

Score:  0.4

Data Source:  BioPlex,STRINGDB

BRD2

Tchem

Family:  Epigenetic

Novelty:  0.00531003

p_int:  0.999999985

p_ni:  1.5e-8

Score:  0.787

Data Source:  BioPlex,STRINGDB

KDM5B

Tchem

Family:  TF; Epigenetic

Novelty:  0.00610414

p_int:  0.999998826

p_ni:  1.57e-7

p_wrong:  0.000001017

Score:  0.309

Data Source:  BioPlex,STRINGDB

RFPL4A

Tdark

Novelty:  0.36360558

p_int:  0.999990875

p_ni:  1.85e-7

p_wrong:  0.00000894

Score:  0.862

Data Source:  BioPlex,STRINGDB

MTMR14

Tbio

Family:  Enzyme

Novelty:  0.07074944

p_int:  0.9949988

p_ni:  0.005001199

p_wrong:  2e-9

Score:  0.234

Data Source:  BioPlex,STRINGDB

FLNA

Tbio

Novelty:  0.00156479

p_int:  0.994417952

p_ni:  0.005582048

Score:  0.234

Data Source:  BioPlex,STRINGDB

RFPL4B

Tdark

Novelty:  2.42779597

p_int:  0.991764634

p_ni:  4e-9

p_wrong:  0.008235362

Data Source:  BioPlex

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (0)

No pathways found

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (0)

No GO Terms found

Disease Associations ()

No disease associations found

GWAS Traits (2)

• Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

5

1 – 2 of 2

GWAS Trait	EFO ID	Study Count	SNP Count	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
velopharyngeal dysfunction	EFO_0009336	1	1	1		21.5
gut microbiome measurement	EFO_0007874	1	1	0	5.6	2.9

• Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

5

1 – 2 of 2

GWAS Trait	EFO ID	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
velopharyngeal dysfunction	EFO_0009336	1		21.5
gut microbiome measurement	EFO_0007874	0	5.6	2.9

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Find similar targets by:

UniProt Keyword Find Similar Targets

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Complete proteome
Polymorphism
Reference proteome

GWAS Trait Find Similar Targets

No Header	No Header
gut microbiome measurement
velopharyngeal dysfunction

IDG Resources

No IDG generated resources found

Orthologs (3)

1 – 3 of 3

Species	Name	Source ID	Gene ID	OMA	EggNOG	Inparanoid
Chimp	family with sequence similarity 90 member A1	VGNC:5377	748455
Mouse	family with sequence similarity 90, member A1B	MGI:1921682	631145
Horse	putative protein FAM90A9P		102149959

Species	Name	OMA	EggNOG	Inparanoid
Chimp	family with sequence similarity 90 member A1
Mouse	family with sequence similarity 90, member A1B
Horse	putative protein FAM90A9P

Publication Statistics

PubMed Score 0.82

PubMed score by year

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PubTator Score 0.25

PubTator score by year

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Related Publications

Text Mined References (7)

Items per page:

10

0 of 0

PMID	Year	Title