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Tbio
FAM84B
Protein FAM84B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000304916
  • ENSP00000302578
  • ENSG00000168672

Symbol
  • BCMP101
  • NSE2
  • NSE2
  • FAM84B
  • BCMP101
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.8
transcription factor binding site profile
0.77
microRNA
0.67
PubMedID
0.64
gene perturbation
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.72   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 260   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.72   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 260   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (36)
IZUMO1
Tbio
Novelty:  0.01839953
p_int:  0.999645758
p_ni:  0.000131399
p_wrong:  0.000222842
Score:  0.187
Data Source:  BioPlex,STRINGDB
GDE1
Tbio
Family:  Enzyme
Novelty:  0.05854843
p_int:  0.999130735
p_ni:  0.000020948
p_wrong:  0.000848317
Score:  0.325
Data Source:  BioPlex,STRINGDB
NMT2
Tchem
Family:  Enzyme
Novelty:  0.04826835
p_int:  0.998824061
p_ni:  0.001175904
p_wrong:  3.5e-8
Score:  0.239
Data Source:  BioPlex,STRINGDB
CTNNA1
Tbio
Novelty:  0.00925774
Score:  0.785
Data Source:  STRINGDB
UROD
Tbio
Family:  Enzyme
Novelty:  0.00337791
Score:  0.766
Data Source:  STRINGDB
ELAC2
Tbio
Family:  Enzyme
Novelty:  0.01234318
Score:  0.721
Data Source:  STRINGDB
REPS1
Tbio
Novelty:  0.08952347
Score:  0.706
Data Source:  STRINGDB
HRASLS
Tbio
Novelty:  0.11804852
Score:  0.691
Data Source:  STRINGDB
BMP2K
Tchem
Family:  Kinase
Novelty:  0.10145601
Score:  0.6
Data Source:  STRINGDB
POU5F1B
Tbio
Family:  TF
Novelty:  0.04634646
Score:  0.586
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum urea measurement
1
3
3
89.1
eosinophil count
2
1
2
24.3
blood urea nitrogen measurement
1
1
1
21.2
myeloid white cell count
1
1
1
9.1
leukocyte count
1
1
1
5.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum urea measurement
3
89.1
eosinophil count
2
24.3
blood urea nitrogen measurement
1
21.2
myeloid white cell count
1
9.1
leukocyte count
1
5.5
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:3026924
399603
Rat
Dog
family with sequence similarity 84 member B
VGNC:40707
102157178
Cow
family with sequence similarity 84 member B
VGNC:28841
540325
Pig
family with sequence similarity 84 member B
100623936
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
family with sequence similarity 84 member B
Cow
family with sequence similarity 84 member B
Pig
family with sequence similarity 84 member B
Publication Statistics
PubMed Score 10.72
PubMed score by year
PubTator Score 6.29
PubTator score by year
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Related Publications
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PMID
Year
Title