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Tdark
FAM81A
Protein FAM81A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000288228
  • ENSP00000288228
  • ENSG00000157470
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.91
histone modification site profile
0.82
cell type or tissue
0.78
microRNA
0.69
tissue sample
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.53   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 68   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.53   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (44)
OR5C1
Tdark
Family:  oGPCR
Novelty:  1.6529517
p_int:  0.968721495
p_ni:  5e-9
p_wrong:  0.0312785
Data Source:  BioPlex
GCNT4
Tbio
Family:  Enzyme
Novelty:  0.23258285
Score:  0.712
Data Source:  STRINGDB
TMED6
Tdark
Novelty:  0.598611
Score:  0.671
Data Source:  STRINGDB
GCNT3
Tbio
Family:  Enzyme
Novelty:  0.04356924
Score:  0.665
Data Source:  STRINGDB
FAM135A
Tdark
Novelty:  0.61758277
Score:  0.662
Data Source:  STRINGDB
GCNT1
Tbio
Family:  Enzyme
Novelty:  0.01487872
Score:  0.651
Data Source:  STRINGDB
CHAC2
Tbio
Family:  Enzyme
Novelty:  0.14706039
Score:  0.603
Data Source:  STRINGDB
FAM171B
Tdark
Novelty:  0.38456365
Score:  0.593
Data Source:  STRINGDB
FAM189A1
Tdark
Novelty:  0.94298311
Score:  0.593
Data Source:  STRINGDB
TMEM179
Tdark
Novelty:  2.21288966
Score:  0.584
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
phosphatidylethanolamine measurement
1
1
1
39.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
phosphatidylethanolamine measurement
1
39.6
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 81 member A
VGNC:3555
453481
Macaque
family with sequence similarity 81 member A
702510
Mouse
MGI:1924136
76886
Rat
RGD:1311958
315789
Dog
family with sequence similarity 81 member A
VGNC:40697
478326
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 81 member A
Macaque
family with sequence similarity 81 member A
Mouse
Rat
Dog
family with sequence similarity 81 member A
Publication Statistics
PubMed Score 2.53
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title