Protein Summary
Involved in ceramide synthesis. This gene encodes a transmembrane protein, which may be a likely target of peroxisome proliferator-activated receptor gamma (PPAR-gamma). The product of the orthologous gene in mouse is related to obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
- ENST00000279389
- ENSP00000279389
- ENSG00000149926
- ENST00000380495
- ENSP00000369863
- FP1188
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.68 | ||
tissue | 0.49 | ||
transcription factor | 0.46 | ||
cell line | 0.45 | ||
cellular component | 0.41 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.02 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 28 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.02 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 28 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0