Tdark FAM53A Protein FAM53A

Protein Summary

Description

May play an important role in neural development; the dorsomedial roof of the third ventricle.

Uniprot Accession IDs

• Q6NSI3
• Q6ZUL5

Gene Name

• FAM53A

Ensembl ID

• ENST00000308132
• ENSP00000310057
• ENSG00000174137
• ENST00000461064
• ENSP00000418243
• ENST00000472884
• ENSP00000426260

Symbol

• DNTNP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.87
tissue sample	0.71
transcription factor	0.7
cell type or tissue	0.68
transcription factor binding site profile	0.66

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.8   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 47   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.8   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 47   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0