Protein Summary
- ENST00000361432
- ENSP00000354688
- ENSG00000119979
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.99 | ||
kinase perturbation | 0.84 | ||
disease perturbation | 0.79 | ||
histone modification site profile | 0.7 | ||
small molecule perturbation | 0.66 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.21 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 41 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.21 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 41 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (40)
COMMD8
Novelty: 0.33240242
p_int: 0.999999999
p_ni: 1e-9
Score: 0.815
Data Source: BioPlex,STRINGDB
COMMD2
Novelty: 0.62195903
p_int: 0.999999995
p_ni: 5e-9
Score: 0.824
Data Source: BioPlex,STRINGDB
COMMD4
Novelty: 0.20453574
p_int: 0.999999981
p_ni: 1.9e-8
Score: 0.866
Data Source: BioPlex,STRINGDB
COMMD9
Novelty: 0.77223999
p_int: 0.999993872
p_ni: 0.000006128
Score: 0.869
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (0)
Disease Associations (null)
GWAS Traits (5)
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
1 | 1 | 1 | 53.3 | ||||||
neutrophil count | 1 | 1 | 1 | 50.6 | |||||
platelet crit | 1 | 1 | 1 | 45.7 | |||||
myeloid white cell count | 1 | 1 | 1 | 45.2 | |||||
BMI-adjusted waist circumference | 1 | 1 | 1 | 21.5 | |||||
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
1 | 53.3 | ||||||
neutrophil count | 1 | 50.6 | |||||
platelet crit | 1 | 45.7 | |||||
myeloid white cell count | 1 | 45.2 | |||||
BMI-adjusted waist circumference | 1 | 21.5 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | family with sequence similarity 45 member A | 465955 | ||||||
Mouse | MGI:1915144 | 67894 | ||||||
Dog | family with sequence similarity 45 member A | VGNC:52990 | 477837 | |||||
Horse | family with sequence similarity 45 member A [Source:HGNC Symbol;Acc:HGNC:31793] | |||||||
Cow | family with sequence similarity 45 member A | 534370 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | family with sequence similarity 45 member A | |||||
Mouse | ||||||
Dog | family with sequence similarity 45 member A | |||||
Horse | family with sequence similarity 45 member A [Source:HGNC Symbol;Acc:HGNC:31793] | |||||
Cow | family with sequence similarity 45 member A | |||||
Publication Statistics
PubMed Score 1.21
PubMed score by year
Related Publications
Text Mined References (6)
Items per page:
0 of 0
PMID | Year | Title |
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