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Tdark
FAM45A
Protein FAM45A

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 41   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 41   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
COMMD1
Tbio
Novelty:  0.01349432
p_int:  1
Score:  0.847
Data Source:  BioPlex,STRINGDB
COMMD10
Tbio
Novelty:  0.29057641
p_int:  1
Score:  0.835
Data Source:  BioPlex,STRINGDB
COMMD3
Tbio
Novelty:  0.07399068
p_int:  1
Score:  0.834
Data Source:  BioPlex,STRINGDB
COMMD6
Tbio
Novelty:  0.11854363
p_int:  1
Score:  0.822
Data Source:  BioPlex,STRINGDB
CCDC22
Tbio
Novelty:  0.01400901
p_int:  1
Score:  0.817
Data Source:  BioPlex,STRINGDB
FAM45BP
Tdark
p_int:  1
Data Source:  BioPlex
COMMD8
Tdark
Novelty:  0.33240242
p_int:  0.999999999
p_ni:  1e-9
Score:  0.815
Data Source:  BioPlex,STRINGDB
COMMD2
Tdark
Novelty:  0.62195903
p_int:  0.999999995
p_ni:  5e-9
Score:  0.824
Data Source:  BioPlex,STRINGDB
COMMD4
Tbio
Novelty:  0.20453574
p_int:  0.999999981
p_ni:  1.9e-8
Score:  0.866
Data Source:  BioPlex,STRINGDB
COMMD9
Tdark
Novelty:  0.77223999
p_int:  0.999993872
p_ni:  0.000006128
Score:  0.869
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
1
53.3
neutrophil count
1
1
1
50.6
platelet crit
1
1
1
45.7
myeloid white cell count
1
1
1
45.2
BMI-adjusted waist circumference
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
53.3
neutrophil count
1
50.6
platelet crit
1
45.7
myeloid white cell count
1
45.2
BMI-adjusted waist circumference
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 45 member A
465955
Mouse
MGI:1915144
67894
Dog
family with sequence similarity 45 member A
VGNC:52990
477837
Horse
family with sequence similarity 45 member A [Source:HGNC Symbol;Acc:HGNC:31793]
Cow
family with sequence similarity 45 member A
534370
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 45 member A
Mouse
Dog
family with sequence similarity 45 member A
Horse
family with sequence similarity 45 member A [Source:HGNC Symbol;Acc:HGNC:31793]
Cow
family with sequence similarity 45 member A
Publication Statistics
PubMed Score 1.21
PubMed score by year
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Related Publications
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PMID
Year
Title