Protein Summary
- ENST00000329759
- ENSP00000371397
- ENSG00000185112
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.85 | ||
transcription factor perturbation | 0.84 | ||
histone modification site profile | 0.61 | ||
small molecule perturbation | 0.58 | ||
microRNA | 0.55 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.09 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 28 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.09 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 28 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (36)
PPP2R5E
Family: Enzyme
Novelty: 0.05974697
p_int: 0.999996459
p_ni: 0.000003541
Score: 0.185
Data Source: BioPlex,STRINGDB
PPP2R5A
Family: Enzyme
Novelty: 0.03073487
p_int: 0.999910867
p_ni: 4.91e-7
p_wrong: 0.000088642
Score: 0.209
Data Source: BioPlex,STRINGDB
PPP2R5B
Family: Enzyme
Novelty: 0.08980945
p_int: 0.999557776
p_ni: 5.7e-8
p_wrong: 0.000442167
Score: 0.268
Data Source: BioPlex,STRINGDB
PPP2R5D
Family: Enzyme
Novelty: 0.03990599
p_int: 0.999127678
p_ni: 0.000863771
p_wrong: 0.000008552
Score: 0.177
Data Source: BioPlex,STRINGDB
CLASP2
Novelty: 0.0353308
p_int: 0.997388565
p_ni: 0.002607536
p_wrong: 0.000003899
Score: 0.243
Data Source: BioPlex,STRINGDB
PPP2R5C
Family: Enzyme
Novelty: 0.03336609
p_int: 0.991609527
p_ni: 0.008390473
Score: 0.211
Data Source: BioPlex,STRINGDB
WRAP53
Family: Enzyme
Novelty: 0.0204638
p_int: 0.916384228
p_ni: 0.083615772
Score: 0.243
Data Source: BioPlex,STRINGDB
PPP2R1B
Family: Enzyme
Novelty: 0.03936638
p_int: 0.799789148
p_ni: 0.200210852
Score: 0.185
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (0)
Disease Associations ()
GWAS Traits (8)
Items per page:
1 – 5 of 8
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
hematocrit | 2 | 2 | 2 | 81.2 | |||||
hemoglobin measurement | 2 | 2 | 2 | 81.1 | |||||
reticulocyte measurement | 3 | 3 | 3 | 79.8 | |||||
reticulocyte count | 2 | 1 | 2 | 70.2 | |||||
eosinophil count | 2 | 2 | 2 | 60.2 | |||||
Items per page:
1 – 5 of 8
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
hematocrit | 2 | 81.2 | |||||
hemoglobin measurement | 2 | 81.1 | |||||
reticulocyte measurement | 3 | 79.8 | |||||
reticulocyte count | 2 | 70.2 | |||||
eosinophil count | 2 | 60.2 | |||||
Find similar targets by:
IDG Resources
Orthologs (8)
1 – 5 of 8
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | family with sequence similarity 43 member A | VGNC:6236 | 460945 | |||||
Macaque | family with sequence similarity 43 member A | 708207 | ||||||
Mouse | MGI:2676309 | 224093 | ||||||
Dog | family with sequence similarity 43 member A | VGNC:53072 | 102152951 | |||||
Cow | family with sequence similarity 43 member A | VGNC:28813 | 539374 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | family with sequence similarity 43 member A | |||||
Macaque | family with sequence similarity 43 member A | |||||
Mouse | ||||||
Dog | family with sequence similarity 43 member A | |||||
Cow | family with sequence similarity 43 member A | |||||
Publication Statistics
PubMed Score 1.09
PubMed score by year
PubTator Score 0.42
PubTator score by year
Related Publications
Text Mined References (5)
Items per page:
0 of 0
PMID | Year | Title |
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