Tbio FAM3C Protein FAM3C

Protein Summary

Description

May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition. This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells. [provided by RefSeq, Mar 2010]

Uniprot Accession IDs

• Q92520
• A6NDN2
• A8K3R7

Gene Name

• FAM3C

Ensembl ID

• ENST00000359943
• ENSP00000353025
• ENSG00000196937

Symbol

• ILEI
• ILEI
• GS3786

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.97
transcription factor binding site profile	0.89
microRNA	0.81
histone modification site profile	0.76
transcription factor perturbation	0.74

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.73   (req: < 5)

Gene RIFs: 27   (req: <= 3)

Antibodies: 247   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.73   (req: >= 5)

Gene RIFs: 27   (req: > 3)

Antibodies: 247   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0