Protein Summary
May act as a defensin against invading fungal microorganisms. This gene encodes a cytokine-like protein. The expression of this gene may be regulated by peroxisome proliferator-activated receptor gamma, and the encoded protein may be involved in the regulation of glucose and lipid metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
- ENST00000359889
- ENSP00000352955
- ENSG00000071889
- ENST00000369643
- ENSP00000358657
- ENST00000393572
- ENSP00000377202
- ENST00000419205
- ENSP00000393086
- ENST00000447601
- ENSP00000416146
- 2-19
- 2.19
- DLD
- 2.19
- XAP-7
- DXS560S
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.9 | ||
virus perturbation | 0.72 | ||
cell type or tissue | 0.62 | ||
gene perturbation | 0.53 | ||
tissue sample | 0.5 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 17.51 (req: < 5)
Gene RIFs: 9 (req: <= 3)
Antibodies: 134 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 17.51 (req: >= 5)
Gene RIFs: 9 (req: > 3)
Antibodies: 134 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0