Tdark FAM32A Protein FAM32A

Protein Summary

Description

Isoform 1, but not isoform 2 or isoform 3, may induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli.

Uniprot Accession IDs

• Q9Y421
• Q9BT02

Gene Name

• FAM32A

Ensembl ID

• ENST00000263384
• ENSP00000263384
• ENSG00000105058
• ENST00000589852
• ENSP00000465969

Symbol

• OTAG12
• OTAG12
• OTAG-12

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.97
transcription factor binding site profile	0.77
kinase perturbation	0.71
histone modification site profile	0.7
cellular component	0.63

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.68   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 45   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.68   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 45   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0