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Tdark
FAM241A
Uncharacterized protein FAM241A

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.84   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 8   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.84   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 8   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (68)
MAN1C1
Tbio
Family:  Enzyme
Novelty:  0.13017812
p_int:  0.999999999
p_wrong:  1e-9
Data Source:  BioPlex
TPBG
Tbio
Novelty:  0.00839213
p_int:  0.999999865
p_ni:  1.5e-8
p_wrong:  1.2e-7
Data Source:  BioPlex
TMEM245
Tdark
Novelty:  0.30094854
p_int:  0.999988545
p_ni:  0.000011431
p_wrong:  2.4e-8
Data Source:  BioPlex
RPN2
Tbio
Family:  Enzyme
Novelty:  0.01796569
p_int:  0.999979044
p_ni:  0.000020956
Data Source:  BioPlex
MAN1A1
Tbio
Family:  Enzyme
Novelty:  0.00645679
p_int:  0.999934346
p_ni:  0.000065654
Data Source:  BioPlex
RTN2
Tbio
Novelty:  0.05184418
p_int:  0.999860008
p_ni:  0.000139972
p_wrong:  2e-8
Data Source:  BioPlex
MAN1A2
Tbio
Family:  Enzyme
Novelty:  0.15637608
p_int:  0.999809548
p_ni:  0.000190449
p_wrong:  3e-9
Data Source:  BioPlex
CLEC10A
Tbio
Novelty:  0.00656565
p_int:  0.999727063
p_ni:  0.000272935
p_wrong:  3e-9
Score:  0.513
Data Source:  BioPlex,STRINGDB
RTN4
Tbio
Novelty:  0.00080371
p_int:  0.999720597
p_ni:  0.000279388
p_wrong:  1.5e-8
Score:  0.669
Data Source:  BioPlex,STRINGDB
COX18
Tbio
Novelty:  0.06288021
p_int:  0.999661496
p_ni:  0.000100195
p_wrong:  0.000238309
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
2
2
89.1
lymphocyte percentage of leukocytes
1
1
1
73.7
neutrophil percentage of leukocytes
1
1
1
67.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
89.1
lymphocyte percentage of leukocytes
1
73.7
neutrophil percentage of leukocytes
1
67.1
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 241 member A
VGNC:2939
737761
Mouse
MGI:1917867
70617
Rat
RGD:1593351
691931
Dog
family with sequence similarity 241 member A
VGNC:40674
610658
Horse
family with sequence similarity 241 member A
VGNC:17866
100629547
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 241 member A
Mouse
Rat
Dog
family with sequence similarity 241 member A
Horse
family with sequence similarity 241 member A
Publication Statistics
PubMed Score 0.84
PubMed score by year
PubTator Score 0.13
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title