Tdark FAM219A Protein FAM219A

Protein Summary

Description

The protein encoded by this gene has homologs that have been identified in mouse, macaque, etc organisms. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

Uniprot Accession IDs

• Q8IW50
• A2A364
• B4DFE1
• B4DSR8
• Q5T590
• Q5T591
• Q5T592
• Q5T594
• Q5T595
• Q8TAZ8

Gene Name

• FAM219A

Ensembl ID

• ENST00000297620
• ENSP00000297620
• ENSG00000164970
• ENST00000445726
• ENSP00000392452

Symbol

• C9orf25
• C9orf25

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
ligand (protein) perturbation	0.83
co-expressed gene	0.69
histone modification site profile	0.64
microRNA	0.6
transcription factor binding site profile	0.57

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.07   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 74   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.07   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 74   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0