You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
FAM208B
Protein FAM208B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000328090
  • ENSP00000328426
  • ENSG00000108021

Symbol
  • C10orf18
  • KIAA2006
  • FAM208B
  • C10orf18
  • bA318E3.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.6
cell line
0.58
tissue sample
0.57
transcription factor binding site profile
0.57
cellular component
0.51


Protein Classes
 No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.6   (req: < 5)
View Publications
Gene RIFs: 0   (req: <= 3)
Antibodies: 27   (req: <= 50)
View Antibodies
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.6   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
 No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
View Data
Go To Tool
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
Go To Tool
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
Go To Tool
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Go To Tool
Approved Drugs (0)
 No approved drugs found
Active Ligands (0)
 No active ligands found
Protein-Protein Interactions (34)
1 – 10 of 34
ERH
Tbio
Novelty:  0.00711649
p_int:  0.999999957
p_ni:  4.3e-8
Score:  0.187
Data Source:  BioPlex,STRINGDB
ZNF597
Tbio
Family:  TF
Novelty:  0.04420398
p_int:  0.999999825
p_ni:  1.53e-7
p_wrong:  2.2e-8
Score:  0.28
Data Source:  BioPlex,STRINGDB
IRF2
Tbio
Family:  TF
Novelty:  0.00534484
p_int:  0.999995182
p_ni:  0.000004818
Score:  0.243
Data Source:  BioPlex,STRINGDB
ZNF200
Tdark
Family:  TF
Novelty:  0.69520683
p_int:  0.999974056
p_ni:  0.000025944
Score:  0.536
Data Source:  BioPlex,STRINGDB
DAXX
Tbio
Novelty:  0.00348585
p_int:  0.999950764
p_ni:  0.000049236
Data Source:  BioPlex
L3MBTL1
Tchem
Family:  TF; Epigenetic
Novelty:  0.02321712
p_int:  0.999683843
p_ni:  0.000316157
Score:  0.181
Data Source:  BioPlex,STRINGDB
TSGA10IP
Tdark
Novelty:  20.75428866
p_int:  0.999256394
p_ni:  0.000742811
p_wrong:  7.96e-7
Data Source:  BioPlex
HNRNPLL
Tbio
Novelty:  0.0498467
p_int:  0.995825531
p_ni:  0.004172778
p_wrong:  0.000001692
Data Source:  BioPlex
NCAPH2
Tbio
Novelty:  0.12134933
p_int:  0.986184383
p_ni:  0.013793607
p_wrong:  0.00002201
Data Source:  BioPlex
MFAP4
Tbio
Novelty:  0.02023782
p_int:  0.981427655
p_ni:  0.018571555
p_wrong:  7.9e-7
Data Source:  BioPlex
Nearest Tclin Targets
 Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
 No pathways found
Viral Interactions (0)
 No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
cytosol
Inferred from Direct Assay (IDA)
HPA
nucleoplasm
Inferred from Direct Assay (IDA)
HPA
nucleus
Inferred from Direct Assay (IDA)
HPA
Disease Associations (null)
 No disease associations found
GWAS Traits (5)
Items per page:
1 – 5 of 5
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
EFO_0004343
1
1
1
36.5
monocyte count
EFO_0005091
1
1
1
31.1
systolic blood pressure
EFO_0006335
1
1
1
17.8
age at menopause
EFO_0004704
1
1
1
15.8
heel bone mineral density
EFO_0009270
1
1
1
7
Items per page:
1 – 5 of 5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
EFO_0004343
1
36.5
monocyte count
EFO_0005091
1
31.1
systolic blood pressure
EFO_0006335
1
17.8
age at menopause
EFO_0004704
1
15.8
heel bone mineral density
EFO_0009270
1
7
IDG Resources
 No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 208 member B
VGNC:3853
450282
Macaque
family with sequence similarity 208 member B
722528
Mouse
family with sequence similarity 208, member B
MGI:2145274
105203
Rat
family with sequence similarity 208, member B
RGD:1564456
361269
Dog
family with sequence similarity 208 member B
VGNC:40653
478015
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 208 member B
Macaque
family with sequence similarity 208 member B
Mouse
family with sequence similarity 208, member B
Rat
family with sequence similarity 208, member B
Dog
family with sequence similarity 208 member B
Publication Statistics
PubMed Score 0.60
PubMed score by year
PubTator Score 0.21
PubTator score by year
Related Publications
Items per page:
0 of 0
PMID
Year
Title