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Tdark
FAM193A
Protein FAM193A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000324666
  • ENSP00000324587
  • ENSG00000125386
  • ENST00000382839
  • ENSP00000372290
  • ENST00000502458
  • ENSP00000427505
  • ENST00000505311
  • ENSP00000421200
  • ENST00000512465
  • ENSP00000423852
  • ENST00000545951
  • ENSP00000443617

Symbol
  • C4orf8
  • C4orf8
  • RES4-22
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.84
virus perturbation
0.83
kinase perturbation
0.71
disease perturbation
0.68
cell line
0.66


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.83   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.83   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (8)
SYCE1
Tbio
Novelty:  0.05038876
p_int:  0.999999939
p_ni:  6.1e-8
p_wrong:  1e-9
Data Source:  BioPlex
MDM4
Tchem
Novelty:  0.00321558
p_int:  0.999999798
p_ni:  2e-7
p_wrong:  1e-9
Score:  0.39
Data Source:  BioPlex,STRINGDB
CHCHD4
Tbio
Novelty:  0.01204944
p_int:  0.999994242
p_ni:  0.000005631
p_wrong:  1.27e-7
Data Source:  BioPlex
NOP14
Tbio
Novelty:  0.08903014
Score:  0.664
Data Source:  STRINGDB
RNF26
Tbio
Novelty:  0.40088751
Score:  0.531
Data Source:  STRINGDB
TMEM175
Tbio
Novelty:  0.07230682
Score:  0.53
Data Source:  STRINGDB
SH3BP2
Tbio
Novelty:  0.00968437
Score:  0.453
Data Source:  STRINGDB
NAT8L
Tbio
Family:  Enzyme
Novelty:  0.01761988
Score:  0.42
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
systolic blood pressure
1
1
1
69.5
self reported educational attainment
3
2
2
5.5
65.3
cognitive function measurement
3
1
3
53.7
intelligence
4
2
1
6
50.6
aging
1
1
1
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
systolic blood pressure
1
69.5
self reported educational attainment
2
5.5
65.3
cognitive function measurement
3
53.7
intelligence
1
6
50.6
aging
1
49.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 193 member A
VGNC:2992
461078
Macaque
family with sequence similarity 193 member A
710992
Mouse
MGI:2447768
231128
Rat
RGD:1309634
305452
Dog
family with sequence similarity 193 member A
VGNC:40641
610546
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 193 member A
Macaque
family with sequence similarity 193 member A
Mouse
Rat
Dog
family with sequence similarity 193 member A
Publication Statistics
PubMed Score 2.83
PubMed score by year
PubTator Score 1.39
PubTator score by year
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Related Publications
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PMID
Year
Title