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Tdark
FAM185A
Protein FAM185A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000409231
  • ENSP00000387066
  • ENSG00000222011
  • ENST00000413034
  • ENSP00000395340
  • ENST00000442873
  • ENSP00000410226
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.86
tissue sample
0.62
virus perturbation
0.59
transcription factor binding site profile
0.58
cell type or tissue
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.31   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 36   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.31   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (9)
NDUFV3
Tclin
Family:  Enzyme
Novelty:  0.15352039
p_int:  0.99999999
p_ni:  9e-9
Data Source:  BioPlex
C12orf66
Tbio
Novelty:  1.38775963
Score:  0.669
Data Source:  STRINGDB
TMEM65
Tdark
Novelty:  0.35968506
Score:  0.643
Data Source:  STRINGDB
FBXL13
Tdark
Novelty:  0.33362589
Score:  0.563
Data Source:  STRINGDB
NOL4
Tbio
Novelty:  0.04108058
Score:  0.54
Data Source:  STRINGDB
C1orf112
Tdark
Novelty:  1.42922586
Score:  0.514
Data Source:  STRINGDB
AKR1D1
Tbio
Family:  Enzyme
Novelty:  0.01264297
Score:  0.474
Data Source:  STRINGDB
PLCL1
Tbio
Family:  Enzyme
Novelty:  0.0388099
Score:  0.445
Data Source:  STRINGDB
FBXL3
Tbio
Novelty:  0.05042679
Score:  0.443
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
chronotype measurement
2
6
4
1
96.1
2
2
0
1.1
51.7
circadian rhythm
1
1
0
1.1
28.1
mental or behavioural disorder
1
1
0
10.7
24.5
1
1
0
10.7
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
chronotype measurement
4
1
96.1
0
1.1
51.7
circadian rhythm
0
1.1
28.1
mental or behavioural disorder
0
10.7
24.5
0
10.7
24.5
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 185 member A
VGNC:4347
742650
Mouse
MGI:2140983
330050
Dog
family with sequence similarity 185 member A
VGNC:40635
475901
Horse
family with sequence similarity 185 member A [Source:HGNC Symbol;Acc:HGNC:22412]
Cow
family with sequence similarity 185 member A
VGNC:28767
531996
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 185 member A
Mouse
Dog
family with sequence similarity 185 member A
Horse
family with sequence similarity 185 member A [Source:HGNC Symbol;Acc:HGNC:22412]
Cow
family with sequence similarity 185 member A
Publication Statistics
PubMed Score 0.31
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title