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Tdark
FAM184A
Protein FAM184A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000338891
  • ENSP00000342604
  • ENSG00000111879
  • ENST00000352896
  • ENSP00000326608
  • ENST00000521531
  • ENSP00000430442

Symbol
  • C6orf60
  • C6orf60
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.86
tissue sample
0.64
small molecule perturbation
0.6
tissue
0.55
transcription factor binding site profile
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.33   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.33   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (14)
CDR2
Tbio
Novelty:  0.00141419
p_int:  0.999999988
p_ni:  3e-9
p_wrong:  9e-9
Score:  0.224
Data Source:  BioPlex,STRINGDB
LRRC61
Tdark
Novelty:  1.45343096
p_int:  0.99999982
p_ni:  1.8e-7
Data Source:  BioPlex
PLEKHO2
Tdark
Novelty:  0.48296621
p_int:  0.999996073
p_ni:  0.000003911
p_wrong:  1.6e-8
Score:  0.332
Data Source:  BioPlex,STRINGDB
PROM2
Tbio
Novelty:  0.0446718
Score:  0.62
Data Source:  STRINGDB
CEP95
Tdark
Novelty:  1.18897795
Score:  0.566
Data Source:  STRINGDB
CAMTA2
Tbio
Family:  TF
Novelty:  0.06741618
Score:  0.557
Data Source:  STRINGDB
ANAPC7
Tbio
Family:  Enzyme
Novelty:  0.17956785
Score:  0.526
Data Source:  STRINGDB
CEP250
Tbio
Novelty:  0.08014712
Score:  0.512
Data Source:  STRINGDB
LRRC8D
Tbio
Novelty:  0.10536285
Score:  0.497
Data Source:  STRINGDB
C9orf131
Tdark
Novelty:  17.32394366
Score:  0.494
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
3
3
3
77.8
mean platelet volume
2
1
2
76.1
testosterone measurement
1
1
1
74.5
mathematical ability
2
2
2
69.6
dehydroepiandrosterone sulphate measurement
1
1
2
51.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
3
77.8
mean platelet volume
2
76.1
testosterone measurement
1
74.5
mathematical ability
2
69.6
dehydroepiandrosterone sulphate measurement
2
51.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 184 member A
VGNC:2822
472112
Macaque
family with sequence similarity 184 member A
714658
Mouse
MGI:1923156
75906
Rat
RGD:1311294
361853
Dog
family with sequence similarity 184 member A
VGNC:40633
476274
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 184 member A
Macaque
family with sequence similarity 184 member A
Mouse
Rat
Dog
family with sequence similarity 184 member A
Publication Statistics
PubMed Score 0.33
PubMed score by year
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Related Publications
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0 of 0
PMID
Year
Title