You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
FAM172A
Cotranscriptional regulator FAM172A

Protein Summary
Description
Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000395965
  • ENSP00000379294
  • ENSG00000113391
  • ENST00000505869
  • ENSP00000426284
  • ENST00000509163
  • ENSP00000423841

Symbol
  • C5orf21
  • Toupee
  • C5orf21
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.99
histone modification site profile
0.89
transcription factor binding site profile
0.65
cell type or tissue
0.62
cell line
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.78   (req: < 5)
Gene RIFs: 13   (req: <= 3)
Antibodies: 46   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.78   (req: >= 5)
Gene RIFs: 13   (req: > 3)
Antibodies: 46   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0