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Tdark
FAM160B1
Protein FAM160B1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000369248
  • ENSP00000358251
  • ENSG00000151553
  • ENST00000369250
  • ENSP00000358253

Symbol
  • KIAA1600
  • KIAA1600
  • bA106M7.3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.84
small molecule perturbation
0.75
microRNA
0.74
transcription factor binding site profile
0.74
virus perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.42   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 111   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.42   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 111   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (45)
TNFSF13B
Tclin
Novelty:  0.00069885
p_int:  0.999999965
p_ni:  2.7e-8
p_wrong:  8e-9
Score:  0.197
Data Source:  BioPlex,STRINGDB
KLHL2
Tbio
Novelty:  0.07279226
p_int:  0.999997403
p_ni:  0.000002597
Data Source:  BioPlex
FAM9B
Tdark
Novelty:  0.39508009
p_int:  0.999978623
p_ni:  9.89e-7
p_wrong:  0.000020389
Data Source:  BioPlex
POC5
Tbio
Novelty:  0.09211907
p_int:  0.999770027
p_ni:  0.000229973
Score:  0.219
Data Source:  BioPlex,STRINGDB
PNKD
Tbio
Family:  Enzyme
Novelty:  0.02456078
p_int:  0.948232938
p_ni:  0.000321483
p_wrong:  0.051445579
Data Source:  BioPlex
TRUB1
Tbio
Family:  Enzyme
Novelty:  0.07013834
Score:  0.753
Data Source:  STRINGDB
FCF1
Tdark
Novelty:  0.04202976
Score:  0.71
Data Source:  STRINGDB
ATRNL1
Tdark
Novelty:  0.28010731
Score:  0.657
Data Source:  STRINGDB
FRMPD2
Tbio
Novelty:  0.40302485
Score:  0.646
Data Source:  STRINGDB
PTGFRN
Tbio
Novelty:  0.02271483
Score:  0.577
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
2
2
1
5.9
78.7
lifestyle measurement
1
1
1
39.6
1
1
0
1.1
21.5
1
1
0
1.1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
1
5.9
78.7
lifestyle measurement
1
39.6
0
1.1
21.5
0
1.1
21.5
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 160 member B1
VGNC:12325
450754
Mouse
MGI:2147545
226252
Rat
RGD:1306116
361774
Dog
family with sequence similarity 160 member B1
VGNC:40608
486899
Horse
family with sequence similarity 160 member B1
VGNC:51500
100068002
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 160 member B1
Mouse
Rat
Dog
family with sequence similarity 160 member B1
Horse
family with sequence similarity 160 member B1
Publication Statistics
PubMed Score 3.42
PubMed score by year
PubTator Score 1.36
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title