Tbio FAM160A2 FTS and Hook-interacting protein

Protein Summary

Description

Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). The protein encoded by this gene is part of the FTS/Hook/FHIP (FHF) complex, which can interact with members of the homotypic vesicular protein sorting (HOPS) complex. This interaction suggests that the encoded protein is involved in vesicle trafficking. [provided by RefSeq, Dec 2016]

Uniprot Accession IDs

• Q8N612
• Q9C0A4
• Q9H0N3
• Q9H624
• FHIP

Gene Name

• FAM160A2

Ensembl ID

• ENST00000265978
• ENSP00000265978
• ENSG00000051009
• ENST00000449352
• ENSP00000416918

Symbol

• C11orf56
• KIAA1759
• FHIP
• C11orf56

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.9
histone modification site profile	0.86
kinase perturbation	0.84
tissue sample	0.7
transcription factor binding site profile	0.58

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.05   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 44   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.05   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 44   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0