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Tdark
FAM153B
Protein FAM153B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000253490
  • ENSP00000253490
  • ENSG00000182230
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
1
microRNA
0.62
tissue
0.54
cellular component
0.52
tissue sample
0.43


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 73   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (20)
FAM153A
Tdark
Novelty:  16.01889363
p_int:  0.999999588
p_wrong:  4.11e-7
Score:  0.66
Data Source:  BioPlex,STRINGDB
ANKRD13D
Tdark
Novelty:  2.14380936
p_int:  0.999995621
p_ni:  0.000004379
Score:  0.169
Data Source:  BioPlex,STRINGDB
MAP1A
Tbio
Novelty:  0.00660165
p_int:  0.998969157
p_ni:  0.000694463
p_wrong:  0.000336379
Score:  0.199
Data Source:  BioPlex,STRINGDB
ANKRD13A
Tbio
Novelty:  0.61940334
p_int:  0.979155279
p_ni:  0.020844721
Score:  0.161
Data Source:  BioPlex,STRINGDB
ZGPAT
Tbio
Family:  Epigenetic
Novelty:  0.16971298
p_int:  0.959863848
p_ni:  0.040094734
p_wrong:  0.000041418
Score:  0.19
Data Source:  BioPlex,STRINGDB
ARMT1
Tbio
Family:  Enzyme
Novelty:  0.19632869
p_int:  0.941778591
p_ni:  0.058209991
p_wrong:  0.000011418
Score:  0.188
Data Source:  BioPlex,STRINGDB
CAMK1
Tchem
Family:  Kinase
Novelty:  0.01239891
p_int:  0.935116293
p_ni:  0.064883707
Score:  0.19
Data Source:  BioPlex,STRINGDB
TAF7
Tbio
Novelty:  0.05316615
p_int:  0.906429016
p_ni:  0.092106237
p_wrong:  0.001464747
Score:  0.239
Data Source:  BioPlex,STRINGDB
C1orf226
Tdark
Novelty:  3.45031712
Score:  0.567
Data Source:  STRINGDB
CFAP77
Tdark
Novelty:  4.08287895
Score:  0.55
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
4
4
91.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
91.8
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.27
PubMed score by year
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Related Publications
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PMID
Year
Title