Tdark FAM153B Protein FAM153B

Protein Summary

Uniprot Accession IDs

• P0C7A2
• A8MTI1

Gene Name

• FAM153B

Ensembl ID

• ENST00000253490
• ENSP00000253490
• ENSG00000182230

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
co-expressed gene	1
microRNA	0.62
tissue	0.54
cellular component	0.52
tissue sample	0.43

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 73   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Expression Data (0 Tissues)

tutorial

No expression data found

Protein Sequence and Structure

Residue Counts

Protein Sequence

Find Targets by Sequence

Show Full Sequence

ProtVista Viewer

Related Tools (4)

Target Illumination GWAS Analytics (TIGA)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

Go To Tool

GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

Go To Tool

GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

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ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

Go To Tool

Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (20)

Explore Interacting Targets

1 – 10 of 20

• See Interactions on String-DB

FAM153A

Tdark

Novelty:  16.01889363

p_int:  0.999999588

p_wrong:  4.11e-7

Score:  0.66

Data Source:  BioPlex,STRINGDB

ANKRD13D

Tdark

Novelty:  2.14380936

p_int:  0.999995621

p_ni:  0.000004379

Score:  0.169

Data Source:  BioPlex,STRINGDB

MAP1A

Tbio

Novelty:  0.00660165

p_int:  0.998969157

p_ni:  0.000694463

p_wrong:  0.000336379

Score:  0.199

Data Source:  BioPlex,STRINGDB

ANKRD13A

Tbio

Novelty:  0.61940334

p_int:  0.979155279

p_ni:  0.020844721

Score:  0.161

Data Source:  BioPlex,STRINGDB

ZGPAT

Tbio

Family:  Epigenetic

Novelty:  0.16971298

p_int:  0.959863848

p_ni:  0.040094734

p_wrong:  0.000041418

Score:  0.19

Data Source:  BioPlex,STRINGDB

ARMT1

Tbio

Family:  Enzyme

Novelty:  0.19632869

p_int:  0.941778591

p_ni:  0.058209991

p_wrong:  0.000011418

Score:  0.188

Data Source:  BioPlex,STRINGDB

CAMK1

Tchem

Family:  Kinase

Novelty:  0.01239891

p_int:  0.935116293

p_ni:  0.064883707

Score:  0.19

Data Source:  BioPlex,STRINGDB

TAF7

Tbio

Novelty:  0.05316615

p_int:  0.906429016

p_ni:  0.092106237

p_wrong:  0.001464747

Score:  0.239

Data Source:  BioPlex,STRINGDB

C1orf226

Tdark

Novelty:  3.45031712

Score:  0.567

Data Source:  STRINGDB

CFAP77

Tdark

Novelty:  4.08287895

Score:  0.55

Data Source:  STRINGDB

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (0)

No pathways found

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (0)

No GO Terms found

Disease Associations (null)

No disease associations found

GWAS Traits (1)

• Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

5

1 – 1 of 1

GWAS Trait	EFO ID	Study Count	SNP Count	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
red blood cell distribution width	EFO_0005192	4	4	4		91.8

• Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

5

1 – 1 of 1

GWAS Trait	EFO ID	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
red blood cell distribution width	EFO_0005192	4		91.8

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UniProt Keyword Find Similar Targets

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Alternative splicing
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GWAS Trait Find Similar Targets

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red blood cell distribution width

IDG Resources

No IDG generated resources found

Orthologs

No orthologs found

Publication Statistics

PubMed Score 0.27

PubMed score by year

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Related Publications

Text Mined References (4)

Items per page:

10

0 of 0

PMID	Year	Title