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Tdark
FAM149B1
Protein FAM149B1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000242505
  • ENSP00000242505
  • ENSG00000138286

Symbol
  • KIAA0974
  • KIAA0974
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.97
histone modification site profile
0.9
virus perturbation
0.85
transcription factor binding site profile
0.84
transcription factor
0.73


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.63   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 54   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.63   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 54   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (12)
TBC1D32
Tbio
Novelty:  0.25744084
p_int:  0.99999989
p_ni:  1.07e-7
p_wrong:  4e-9
Score:  0.912
Data Source:  BioPlex,STRINGDB
CFAP20
Tbio
Novelty:  0.01299681
p_int:  0.991489326
p_ni:  0.008510674
Score:  0.869
Data Source:  BioPlex,STRINGDB
DNAJC9
Tbio
Novelty:  0.25748073
Score:  0.937
Data Source:  STRINGDB
CFAP70
Tdark
Novelty:  1.0349863
Score:  0.53
Data Source:  STRINGDB
SUPT7L
Tbio
Novelty:  0.20661559
Score:  0.475
Data Source:  STRINGDB
NUDT13
Tdark
Novelty:  0.93681906
Score:  0.445
Data Source:  STRINGDB
USP54
Tdark
Family:  Enzyme
Novelty:  0.31344498
Score:  0.44
Data Source:  STRINGDB
ABRAXAS2
Tbio
Novelty:  0.20430604
Score:  0.418
Data Source:  STRINGDB
MSS51
Tbio
Novelty:  0.06388791
Score:  0.416
Data Source:  STRINGDB
FARP1
Tbio
Novelty:  0.04040696
Score:  0.405
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
1
1
53.5
glomerular filtration rate
1
1
1
39.7
reticulocyte measurement
1
1
1
25.8
high density lipoprotein cholesterol measurement
1
1
1
13.5
free cholesterol:total lipids ratio
1
1
1
13.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
53.5
glomerular filtration rate
1
39.7
reticulocyte measurement
1
25.8
high density lipoprotein cholesterol measurement
1
13.5
free cholesterol:total lipids ratio
1
13.5
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 149 member B1
VGNC:3847
453673
Macaque
family with sequence similarity 149 member B1
707485
Mouse
MGI:2145567
105428
Rat
RGD:1359592
289900
Dog
family with sequence similarity 149 member B1
VGNC:40600
609882
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 149 member B1
Macaque
family with sequence similarity 149 member B1
Mouse
Rat
Dog
family with sequence similarity 149 member B1
Publication Statistics
PubMed Score 2.63
PubMed score by year
PubTator Score 0.17
PubTator score by year
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Related Publications
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PMID
Year
Title