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Tdark
FAM135A
Protein FAM135A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361499
  • ENSP00000354913
  • ENSG00000082269
  • ENST00000370479
  • ENSP00000359510
  • ENST00000418814
  • ENSP00000410768
  • ENST00000457062
  • ENSP00000409201
  • ENST00000505868
  • ENSP00000423307

Symbol
  • KIAA1411
  • KIAA1411
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.98
kinase perturbation
0.93
histone modification site profile
0.86
transcription factor perturbation
0.8
microRNA
0.76


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.45   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.45   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
ZNF726
Tdark
Family:  TF
Novelty:  5.86666667
Score:  0.668
Data Source:  STRINGDB
FAM81A
Tdark
Novelty:  0.6165039
Score:  0.662
Data Source:  STRINGDB
ZRANB1
Tbio
Family:  Enzyme
Novelty:  0.07721072
Score:  0.66
Data Source:  STRINGDB
TMED6
Tdark
Novelty:  0.598611
Score:  0.643
Data Source:  STRINGDB
CHAC2
Tbio
Family:  Enzyme
Novelty:  0.14706039
Score:  0.6
Data Source:  STRINGDB
ZNF727
Tdark
Novelty:  4.69608864
Score:  0.584
Data Source:  STRINGDB
TEX30
Tdark
Novelty:  0.69754742
Score:  0.582
Data Source:  STRINGDB
MTRNR2L12
Tdark
Novelty:  1.05717232
Score:  0.581
Data Source:  STRINGDB
MTRNR2L8
Tdark
Novelty:  0.24759379
Score:  0.581
Data Source:  STRINGDB
ABHD13
Tdark
Family:  Enzyme
Novelty:  2.01646617
Score:  0.58
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
2
2
55.5
type 2 diabetes mellitus
1
1
0
1.5
44.9
mean platelet volume
2
1
2
16.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
2
55.5
type 2 diabetes mellitus
0
1.5
44.9
mean platelet volume
2
16.5
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 135 member A
VGNC:2820
472050
Macaque
family with sequence similarity 135 member A
714862
Mouse
MGI:1915437
68187
Rat
RGD:1304927
367235
Dog
family with sequence similarity 135 member A
VGNC:40594
474960
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 135 member A
Macaque
family with sequence similarity 135 member A
Mouse
Rat
Dog
family with sequence similarity 135 member A
Publication Statistics
PubMed Score 1.45
PubMed score by year
PubTator Score 0.75
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title