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Tdark
FAM118B
Protein FAM118B

Protein Summary
Description
May play a role in Cajal bodies formation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000533050
  • ENSP00000433343
  • ENSG00000197798
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.95
histone modification site profile
0.89
transcription factor perturbation
0.68
tissue sample
0.62
transcription factor binding site profile
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.59   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 132   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.59   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 132   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (44)
FAS
Tbio
Novelty:  0.00043286
p_int:  0.999986481
p_ni:  0.000013519
Data Source:  BioPlex
SCN2B
Tbio
Family:  IC
Novelty:  0.03773629
p_int:  0.999482488
p_ni:  0.000517512
Data Source:  BioPlex
GLMP
Tdark
Novelty:  0.10163099
p_int:  0.999448304
p_ni:  0.000551696
Data Source:  BioPlex
DECR1
Tbio
Family:  Enzyme
Novelty:  0.02699187
p_int:  0.99940519
p_ni:  0.00059481
Score:  0.188
Data Source:  BioPlex,STRINGDB
KCNJ6
Tchem
Family:  IC
Novelty:  0.00330353
p_int:  0.99934864
p_ni:  0.000651259
p_wrong:  1.01e-7
Score:  0.173
Data Source:  BioPlex,STRINGDB
LAGE3
Tdark
Novelty:  0.02099961
p_int:  0.998463295
p_ni:  0.001536637
p_wrong:  6.8e-8
Data Source:  BioPlex
TMEM9
Tbio
Novelty:  0.06916197
p_int:  0.998200876
p_ni:  0.001798928
p_wrong:  1.95e-7
Data Source:  BioPlex
FAM174A
Tdark
Novelty:  0.30693139
p_int:  0.995971985
p_ni:  0.004028008
p_wrong:  7e-9
Data Source:  BioPlex
BSG
Tbio
Novelty:  0.0010285
p_int:  0.993942735
p_ni:  0.006057265
Data Source:  BioPlex
LAMP2
Tbio
Novelty:  0.00168009
p_int:  0.993513547
p_ni:  0.006486453
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (24)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
7
8
10
98.3
apolipoprotein B measurement
2
7
7
98
total cholesterol measurement
2
4
5
94.2
calcium measurement
1
2
2
91.9
ST2 protein measurement
1
1
1
81.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
10
98.3
apolipoprotein B measurement
7
98
total cholesterol measurement
5
94.2
calcium measurement
2
91.9
ST2 protein measurement
1
81.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 118 member B
VGNC:3273
466843
Macaque
family with sequence similarity 118 member B
714323
Mouse
MGI:1924483
109229
Rat
RGD:1307173
315549
Dog
family with sequence similarity 118 member B
VGNC:40585
489294
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 118 member B
Macaque
family with sequence similarity 118 member B
Mouse
Rat
Dog
family with sequence similarity 118 member B
Publication Statistics
PubMed Score 1.59
PubMed score by year
PubTator Score 1.10
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title