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Tdark
FAM117A
Protein FAM117A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000240364
  • ENSP00000240364
  • ENSG00000121104
  • ENST00000513602
  • ENSP00000465808
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.76
transcription factor binding site profile
0.75
transcription factor perturbation
0.68
tissue sample
0.67
transcription factor
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.51   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 46   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.51   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 46   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (19)
PICK1
Tbio
Novelty:  0.0058265
p_int:  0.999555391
p_ni:  0.0000016
p_wrong:  0.000443009
Score:  0.209
Data Source:  BioPlex,STRINGDB
LRFN2
Tbio
Novelty:  0.07450569
Score:  0.721
Data Source:  STRINGDB
TSSK6
Tbio
Family:  Kinase
Novelty:  0.01684267
Score:  0.609
Data Source:  STRINGDB
MON1B
Tbio
Novelty:  0.13486379
Score:  0.554
Data Source:  STRINGDB
OR2V2
Tdark
Family:  oGPCR
Novelty:  28
Score:  0.537
Data Source:  STRINGDB
SLC46A3
Tbio
Family:  Transporter
Novelty:  0.17902241
Score:  0.52
Data Source:  STRINGDB
DERL1
Tbio
Novelty:  0.01382722
Score:  0.493
Data Source:  STRINGDB
DLX3
Tbio
Family:  TF
Novelty:  0.00887868
Score:  0.471
Data Source:  STRINGDB
ZNF496
Tbio
Family:  TF
Novelty:  0.18264818
Score:  0.47
Data Source:  STRINGDB
GMFG
Tbio
Novelty:  0.0893982
Score:  0.447
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
1
4
4
97.8
mean corpuscular volume
3
3
4
96.9
mosaic loss of chromosome Y measurement
3
2
3
86.9
mean corpuscular hemoglobin concentration
1
1
1
85.6
alkaline phosphatase measurement
3
2
2
10.3
78.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
4
97.8
mean corpuscular volume
4
96.9
mosaic loss of chromosome Y measurement
3
86.9
mean corpuscular hemoglobin concentration
1
85.6
alkaline phosphatase measurement
2
10.3
78.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 117 member A
VGNC:9427
455107
Mouse
MGI:2144564
215512
Rat
RGD:1561062
497983
Dog
family with sequence similarity 117 member A
VGNC:40582
609175
Cow
family with sequence similarity 117 member A
VGNC:28719
509931
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 117 member A
Mouse
Rat
Dog
family with sequence similarity 117 member A
Cow
family with sequence similarity 117 member A
Publication Statistics
PubMed Score 0.51
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title