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Tbio
FAM110B
Protein FAM110B

Protein Summary
Description
May be involved in tumor progression.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361488
  • ENSP00000355204
  • ENSG00000169122

Symbol
  • C8orf72
  • C8orf72
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.66
small molecule perturbation
0.57
transcription factor
0.55
transcription factor binding site profile
0.53
co-expressed gene
0.52


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.59   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 72   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.59   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (27)
CSNK1E
Tclin
Family:  Kinase
Novelty:  0.00891859
p_int:  0.999994712
p_ni:  5.1e-7
p_wrong:  0.000004778
Score:  0.726
Data Source:  BioPlex,STRINGDB
CSNK1D
Tchem
Family:  Kinase
Novelty:  0.00896935
p_int:  0.999988067
p_ni:  5.4e-8
p_wrong:  0.000011878
Score:  0.82
Data Source:  BioPlex,STRINGDB
CSPP1
Tbio
Novelty:  0.02734691
Score:  0.93
Data Source:  STRINGDB
ANKRD34B
Tbio
Novelty:  0.12133948
Score:  0.741
Data Source:  STRINGDB
PPM1K
Tbio
Family:  Enzyme
Novelty:  0.0337866
Score:  0.714
Data Source:  STRINGDB
UBXN2B
Tbio
Novelty:  0.67291382
Score:  0.631
Data Source:  STRINGDB
TOX
Tbio
Family:  TF
Novelty:  0.01478865
Score:  0.6
Data Source:  STRINGDB
SDR16C5
Tbio
Family:  Enzyme
Novelty:  0.11319496
Score:  0.585
Data Source:  STRINGDB
CHCHD7
Tdark
Novelty:  0.03220354
Score:  0.551
Data Source:  STRINGDB
GATM
Tbio
Family:  Enzyme
Novelty:  0.00340356
Score:  0.55
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
1
2
2
54.3
low density lipoprotein cholesterol measurement
1
2
2
49.2
1
1
0
9.8
24.5
serum gamma-glutamyl transferase measurement
1
1
1
7.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
2
54.3
low density lipoprotein cholesterol measurement
2
49.2
0
9.8
24.5
serum gamma-glutamyl transferase measurement
1
7.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1916593
242297
Rat
RGD:1563403
500400
Dog
family with sequence similarity 110 member B
VGNC:40576
102151698
Horse
family with sequence similarity 110 member B
VGNC:17785
100052940
Cow
family with sequence similarity 110 member B
VGNC:28717
767946
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
family with sequence similarity 110 member B
Horse
family with sequence similarity 110 member B
Cow
family with sequence similarity 110 member B
Publication Statistics
PubMed Score 3.59
PubMed score by year
PubTator Score 0.67
PubTator score by year
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Related Publications
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PMID
Year
Title