EXOSC3
Exosome complex component RRP40
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.94 | ||
interacting protein | 0.87 | ||
transcription factor binding site profile | 0.81 | ||
cellular component | 0.76 | ||
histone modification site profile | 0.75 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | ATF4 activates genes in response to endoplasmic reticulum stress | ||||
Reactome | Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | ||||
Reactome | Deadenylation-dependent mRNA decay | ||||
Reactome | KSRP (KHSRP) binds and destabilizes mRNA | ||||
Reactome | Major pathway of rRNA processing in the nucleolus and cytosol | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
ATF4 activates genes in response to endoplasmic reticulum stress | ||||
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | ||||
Deadenylation-dependent mRNA decay | ||||
KSRP (KHSRP) binds and destabilizes mRNA | ||||
Major pathway of rRNA processing in the nucleolus and cytosol | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
reticulocyte count | 2 | 2 | 2 | 47.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
reticulocyte count | 2 | 47.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | exosome component 3 | VGNC:4687 | 465105 | |||||
Macaque | exosome component 3 | 716347 | ||||||
Mouse | MGI:1913612 | 66362 | ||||||
Rat | RGD:1304739 | 313243 | ||||||
Dog | exosome component 3 | VGNC:40524 | 481616 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | exosome component 3 | |||||
Macaque | exosome component 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | exosome component 3 | |||||
PMID | Year | Title |
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