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Tbio
EVI5
Ecotropic viral integration site 5 protein homolog

Protein Summary
Description
Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000370331
  • ENSP00000359356
  • ENSG00000067208
  • ENST00000540033
  • ENSP00000440826

Symbol
  • NB4S
  • NB4S
  • EVI-5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.84
virus perturbation
0.83
disease perturbation
0.79
tissue sample
0.75
transcription factor perturbation
0.74


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.31   (req: < 5)
Gene RIFs: 15   (req: <= 3)
Antibodies: 82   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.31   (req: >= 5)
Gene RIFs: 15   (req: > 3)
Antibodies: 82   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0