You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
EVI2A
Protein EVI2A

Protein Summary
Description
May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000247270
  • ENSP00000247270
  • ENSG00000126860
  • ENST00000461237
  • ENSP00000418064
  • ENST00000462804
  • ENSP00000420557

Symbol
  • EVDA
  • EVI2
  • EVDA
  • EVI2
  • EVI-2A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.95
virus perturbation
0.88
PubMedID
0.8
disease perturbation
0.74
microRNA
0.56


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 42.08   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 70   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 42.08   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (34)
GOPC
Tbio
Novelty:  0.01110168
p_int:  0.974569776
p_ni:  0.025430222
p_wrong:  2e-9
Score:  0.177
Data Source:  BioPlex,STRINGDB
ARL6IP5
Tbio
Novelty:  0.00871985
p_int:  0.913744738
p_ni:  0.086255262
Score:  0.206
Data Source:  BioPlex,STRINGDB
DOK2
Tbio
Novelty:  0.02651438
p_int:  0.864279256
p_ni:  0.135720744
Score:  0.324
Data Source:  BioPlex,STRINGDB
FGFR1
Tclin
Family:  Kinase
Novelty:  0.00055714
p_int:  0.779242138
p_ni:  0.22074956
p_wrong:  0.000008303
Score:  0.184
Data Source:  BioPlex,STRINGDB
NCEH1
Tchem
Family:  Enzyme
Novelty:  0.01528589
p_int:  0.770698173
p_ni:  0.024142626
p_wrong:  0.205159201
Score:  0.248
Data Source:  BioPlex,STRINGDB
EVI2B
Tbio
Novelty:  0.11190124
Score:  0.978
Data Source:  STRINGDB
OMG
Tbio
Novelty:  0.00993333
Score:  0.82
Data Source:  STRINGDB
RNF135
Tbio
Family:  Enzyme
Novelty:  0.05600338
Score:  0.666
Data Source:  STRINGDB
NF1
Tbio
Novelty:  0.00019092
Score:  0.64
Data Source:  STRINGDB
AK3
Tbio
Family:  Kinase
Novelty:  0.02673466
Score:  0.626
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (18)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
4
2
4
90.3
risk-taking behaviour
2
2
2
83.4
3
3
2
1.1
80.7
platelet count
1
1
1
71.9
total cholesterol measurement
3
2
3
71.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
4
90.3
risk-taking behaviour
2
83.4
2
1.1
80.7
platelet count
1
71.9
total cholesterol measurement
3
71.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ecotropic viral integration site 2A
100614092
Macaque
ecotropic viral integration site 2A
713110
Mouse
MGI:95458
14017
Rat
RGD:1593824
685433
Dog
ecotropic viral integration site 2A
100688963
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ecotropic viral integration site 2A
Macaque
ecotropic viral integration site 2A
Mouse
Rat
Dog
ecotropic viral integration site 2A
Publication Statistics
PubMed Score 42.08
PubMed score by year
PubTator Score 14.95
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title