Protein Summary
May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor.
- ENST00000247270
- ENSP00000247270
- ENSG00000126860
- ENST00000461237
- ENSP00000418064
- ENST00000462804
- ENSP00000420557
- EVDA
- EVI2
- EVDA
- EVI2
- EVI-2A
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
gene perturbation | 0.95 | ||
virus perturbation | 0.88 | ||
PubMedID | 0.8 | ||
disease perturbation | 0.74 | ||
microRNA | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 42.08 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 70 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 42.08 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 70 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (34)
GOPC
Novelty: 0.01110168
p_int: 0.974569776
p_ni: 0.025430222
p_wrong: 2e-9
Score: 0.177
Data Source: BioPlex,STRINGDB
ARL6IP5
Novelty: 0.00871985
p_int: 0.913744738
p_ni: 0.086255262
Score: 0.206
Data Source: BioPlex,STRINGDB
DOK2
Novelty: 0.02651438
p_int: 0.864279256
p_ni: 0.135720744
Score: 0.324
Data Source: BioPlex,STRINGDB
FGFR1
Family: Kinase
Novelty: 0.00055714
p_int: 0.779242138
p_ni: 0.22074956
p_wrong: 0.000008303
Score: 0.184
Data Source: BioPlex,STRINGDB
NCEH1
Family: Enzyme
Novelty: 0.01528589
p_int: 0.770698173
p_ni: 0.024142626
p_wrong: 0.205159201
Score: 0.248
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (2)
Functions (1)
Components (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Non-traceable Author Statement (NAS) | UniProtKB | |||
Disease Associations ()
GWAS Traits (18)
Items per page:
1 – 5 of 18
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 4 | 2 | 4 | 90.3 | |||||
risk-taking behaviour | 2 | 2 | 2 | 83.4 | |||||
3 | 3 | 2 | 1.1 | 80.7 | |||||
platelet count | 1 | 1 | 1 | 71.9 | |||||
total cholesterol measurement | 3 | 2 | 3 | 71.6 | |||||
Items per page:
1 – 5 of 18
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 4 | 90.3 | |||||
risk-taking behaviour | 2 | 83.4 | |||||
2 | 1.1 | 80.7 | |||||
platelet count | 1 | 71.9 | |||||
total cholesterol measurement | 3 | 71.6 | |||||
Find similar targets by:
IDG Resources
Orthologs (9)
1 – 5 of 9
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | ecotropic viral integration site 2A | 100614092 | ||||||
Macaque | ecotropic viral integration site 2A | 713110 | ||||||
Mouse | MGI:95458 | 14017 | ||||||
Rat | RGD:1593824 | 685433 | ||||||
Dog | ecotropic viral integration site 2A | 100688963 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | ecotropic viral integration site 2A | |||||
Macaque | ecotropic viral integration site 2A | |||||
Mouse | ||||||
Rat | ||||||
Dog | ecotropic viral integration site 2A | |||||
Publication Statistics
PubMed Score 42.08
PubMed score by year
PubTator Score 14.95
PubTator score by year
Related Publications
Text Mined References (14)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
|---|