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Tdark
EVA1B
Protein eva-1 homolog B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000270824
  • ENSP00000270824
  • ENSG00000142694

Symbol
  • C1orf78
  • FAM176B
  • C1orf78
  • FAM176B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.58
small molecule perturbation
0.56
cell line
0.53
PubMedID
0.53
tissue sample
0.52


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 17   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 17   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (80)
SDC4
Tbio
Novelty:  0.00319073
p_int:  0.999990205
p_ni:  0.000004993
p_wrong:  0.000004802
Data Source:  BioPlex
SLC25A51
Tbio
Family:  Transporter
Novelty:  0.21568087
p_int:  0.999986087
p_ni:  0.000013911
p_wrong:  2e-9
Data Source:  BioPlex
TBC1D10A
Tbio
Novelty:  0.16930827
p_int:  0.999973101
p_ni:  0.000023455
p_wrong:  0.000003443
Score:  0.557
Data Source:  BioPlex,STRINGDB
DCAKD
Tdark
Family:  Enzyme
Novelty:  1.5418995
p_int:  0.999876963
p_ni:  0.000123037
Data Source:  BioPlex
NECAP2
Tdark
Novelty:  0.4141034
p_int:  0.999830194
p_ni:  0.000157732
p_wrong:  0.000012074
Data Source:  BioPlex
CNTNAP1
Tbio
Novelty:  0.00618741
p_int:  0.999805579
p_ni:  0.000192633
p_wrong:  0.000001789
Data Source:  BioPlex
SDC2
Tbio
Novelty:  0.00597758
p_int:  0.999749109
p_ni:  0.000202829
p_wrong:  0.000048062
Data Source:  BioPlex
PTRH2
Tbio
Family:  Enzyme
Novelty:  0.02494576
p_int:  0.999663047
p_ni:  0.000336938
p_wrong:  1.4e-8
Data Source:  BioPlex
TMEM53
Tdark
Novelty:  0.75877723
p_int:  0.999576285
p_ni:  1.4e-8
p_wrong:  0.000423701
Data Source:  BioPlex
RECQL
Tbio
Family:  Enzyme
Novelty:  0.00840137
p_int:  0.99942461
p_ni:  0.000223723
p_wrong:  0.000351667
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
1
1
1
66.2
reticulocyte measurement
3
2
3
64.5
neutrophil count
2
2
2
61
reticulocyte count
2
1
2
53.6
platelet count
2
2
2
47.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
1
66.2
reticulocyte measurement
3
64.5
neutrophil count
2
61
reticulocyte count
2
53.6
platelet count
2
47.6
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
eva-1 homolog B
VGNC:53254
456507
Macaque
eva-1 homolog B
713159
Mouse
MGI:1922063
230752
Rat
RGD:1308876
362597
Dog
eva-1 homolog B
VGNC:54557
608469
Species
Name
OMA
EggNOG
Inparanoid
Chimp
eva-1 homolog B
Macaque
eva-1 homolog B
Mouse
Rat
Dog
eva-1 homolog B
Publication Statistics
PubMed Score 2.00
PubMed score by year
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Related Publications
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PMID
Year
Title