Tbio ESF1 ESF1 homolog

Protein Summary

Description

May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity).

Uniprot Accession IDs

• Q9H501
• Q86X92
• Q9H9Q5
• Q9HA35
• Q9NX93
• Q9P1S6

Gene Name

• ESF1

Ensembl ID

• ENST00000202816
• ENSP00000202816
• ENSG00000089048

Symbol

• ABTAP
• C20orf6
• ABTAP
• C20orf6
• HDCMC28P
• bA526K24.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
hub protein	0.97
drug perturbation	0.96
ligand (protein) perturbation	0.96
interacting protein	0.82
transcription factor binding site profile	0.74

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 34.91   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 65   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 34.91   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0