Tbio ESAM Endothelial cell-selective adhesion molecule

Protein Summary

Description

Can mediate aggregation most likely through a homophilic molecular interaction.

Uniprot Accession IDs

• Q96AP7
• B4DVN8
• Q96T50

Gene Name

• ESAM

Ensembl ID

• ENST00000278927
• ENSP00000278927
• ENSG00000149564
• ENST00000444566
• ENSP00000406689

Symbol

• W117m

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.88
transcription factor perturbation	0.8
protein domain	0.73
tissue sample	0.65
cellular component	0.64

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 185.52   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 403   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 185.52   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 403   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0