ERCC3
General transcription and DNA repair factor IIH helicase subunit XPB
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 1 | ||
biological process | 0.97 | ||
histone modification site profile | 0.9 | ||
disease perturbation | 0.83 | ||
protein domain | 0.73 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | DNA Repair | ||||
Reactome | Disease | ||||
Reactome | Dual Incision in GG-NER | ||||
Reactome | Dual incision in TC-NER | ||||
Reactome | Epigenetic regulation of gene expression | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
DNA Repair | ||||
Disease | ||||
Dual Incision in GG-NER | ||||
Dual incision in TC-NER | ||||
Epigenetic regulation of gene expression | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
protein C measurement | 2 | 3 | 4 | 90.5 | |||||
self reported educational attainment | 1 | 1 | 1 | 4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
protein C measurement | 4 | 90.5 | |||||
self reported educational attainment | 1 | 4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:95414 | 13872 | ||||||
Rat | RGD:1307139 | 291703 | ||||||
Dog | ERCC excision repair 3, TFIIH core complex helicase subunit | VGNC:40443 | 476105 | |||||
Horse | ERCC excision repair 3, TFIIH core complex helicase subunit | VGNC:51454 | 100050708 | |||||
Cow | ERCC excision repair 3, TFIIH core complex helicase subunit | VGNC:28570 | 507984 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | ERCC excision repair 3, TFIIH core complex helicase subunit | |||||
Horse | ERCC excision repair 3, TFIIH core complex helicase subunit | |||||
Cow | ERCC excision repair 3, TFIIH core complex helicase subunit | |||||
PMID | Year | Title |
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