ERCC1
DNA excision repair protein ERCC-1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological term | 0.99 | ||
disease perturbation | 0.96 | ||
kinase perturbation | 0.96 | ||
transcription factor perturbation | 0.94 | ||
biological process | 0.93 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | DNA Double-Strand Break Repair | ||||
Reactome | DNA Repair | ||||
Reactome | Dual Incision in GG-NER | ||||
Reactome | Dual incision in TC-NER | ||||
Reactome | Fanconi Anemia Pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
DNA Double-Strand Break Repair | ||||
DNA Repair | ||||
Dual Incision in GG-NER | ||||
Dual incision in TC-NER | ||||
Fanconi Anemia Pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
creatine kinase measurement | 4 | 4 | 7 | 98.4 | |||||
heel bone mineral density | 3 | 4 | 6 | 91.1 | |||||
apolipoprotein B measurement | 1 | 5 | 5 | 88.7 | |||||
low density lipoprotein cholesterol measurement | 1 | 3 | 3 | 76.7 | |||||
C-reactive protein measurement | 2 | 3 | 3 | 71.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
creatine kinase measurement | 7 | 98.4 | |||||
heel bone mineral density | 6 | 91.1 | |||||
apolipoprotein B measurement | 5 | 88.7 | |||||
low density lipoprotein cholesterol measurement | 3 | 76.7 | |||||
C-reactive protein measurement | 3 | 71.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ERCC excision repair 1, endonuclease non-catalytic subunit | VGNC:2387 | 450179 | |||||
Macaque | ERCC excision repair 1, endonuclease non-catalytic subunit | 574267 | ||||||
Mouse | MGI:95412 | 13870 | ||||||
Rat | RGD:1306992 | 292673 | ||||||
Dog | ERCC excision repair 1, endonuclease non-catalytic subunit | VGNC:40441 | 612282 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ERCC excision repair 1, endonuclease non-catalytic subunit | |||||
Macaque | ERCC excision repair 1, endonuclease non-catalytic subunit | |||||
Mouse | ||||||
Rat | ||||||
Dog | ERCC excision repair 1, endonuclease non-catalytic subunit | |||||
PMID | Year | Title |
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