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Tbio
EPN3
Epsin-3

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.59   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 115   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.59   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 115   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (87)
EPN2
Tbio
Novelty:  0.06405828
p_int:  1
Score:  0.87
Data Source:  BioPlex,STRINGDB
EPN1
Tbio
Novelty:  0.01788784
p_int:  0.999999974
p_ni:  2.6e-8
Score:  0.876
Data Source:  BioPlex,STRINGDB
UBB
Tbio
Novelty:  0.00661254
p_int:  0.999992406
p_ni:  0.000007594
Score:  0.418
Data Source:  BioPlex,STRINGDB
TNKS2
Tchem
Family:  Enzyme
Novelty:  0.00938509
p_int:  0.999980638
p_ni:  0.000019362
Score:  0.159
Data Source:  BioPlex,STRINGDB
MID1
Tbio
Family:  Enzyme
Novelty:  0.02400169
p_int:  0.999978136
p_ni:  0.000021864
Score:  0.219
Data Source:  BioPlex,STRINGDB
CASP2
Tchem
Family:  Enzyme
Novelty:  0.00189892
p_int:  0.999952275
p_ni:  0.000039001
p_wrong:  0.000008724
Score:  0.303
Data Source:  BioPlex,STRINGDB
MID2
Tbio
Family:  Enzyme
Novelty:  0.01349913
p_int:  0.99979066
p_ni:  0.000027522
p_wrong:  0.000181818
Score:  0.207
Data Source:  BioPlex,STRINGDB
TNKS
Tchem
Family:  Enzyme
Novelty:  0.00404545
p_int:  0.999726731
p_ni:  0.000273269
Score:  0.164
Data Source:  BioPlex,STRINGDB
ARIH1
Tbio
Family:  Enzyme
Novelty:  0.0258739
p_int:  0.999624642
p_ni:  0.000375357
p_wrong:  1e-9
Score:  0.248
Data Source:  BioPlex,STRINGDB
CYHR1
Tdark
Novelty:  0.04771996
p_int:  0.999187636
p_ni:  0.000669742
p_wrong:  0.000142622
Score:  0.2
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (10)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
1
1
77.1
risk-taking behaviour
1
2
2
54.2
reticulocyte count
2
2
2
52.3
hip circumference
1
2
2
47.5
triglyceride measurement
1
1
1
42.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
77.1
risk-taking behaviour
2
54.2
reticulocyte count
2
52.3
hip circumference
2
47.5
triglyceride measurement
1
42.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
epsin 3
703075
Mouse
MGI:1919139
71889
Rat
RGD:1306416
360605
Dog
epsin 3
VGNC:40421
491081
Horse
epsin 3
VGNC:17633
100056408
Species
Name
OMA
EggNOG
Inparanoid
Macaque
epsin 3
Mouse
Rat
Dog
epsin 3
Horse
epsin 3
Publication Statistics
PubMed Score 8.59
PubMed score by year
PubTator Score 5.15
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title