EPHX2
Bifunctional epoxide hydrolase 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
PubMedID | 0.97 | ||
transcription factor perturbation | 0.96 | ||
gene perturbation | 0.95 | ||
protein domain | 0.92 | ||
chemical | 0.81 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Arachidonic acid metabolism | ||||
Reactome | Biosynthesis of DHA-derived SPMs | ||||
Reactome | Biosynthesis of maresins | ||||
Reactome | Biosynthesis of specialized proresolving mediators (SPMs) | ||||
Reactome | Fatty acid metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Arachidonic acid metabolism | ||||
Biosynthesis of DHA-derived SPMs | ||||
Biosynthesis of maresins | ||||
Biosynthesis of specialized proresolving mediators (SPMs) | ||||
Fatty acid metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
smoking status measurement | 2 | 4 | 5 | 96.8 | |||||
smoking initiation | 4 | 5 | 5 | 94.8 | |||||
6 | 4 | 0 | 5.9 | 91.7 | |||||
family history of Alzheimer’s disease | 1 | 3 | 0 | 8.3 | 87.3 | ||||
cigarettes per day measurement | 4 | 4 | 5 | 77.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
smoking status measurement | 5 | 96.8 | |||||
smoking initiation | 5 | 94.8 | |||||
0 | 5.9 | 91.7 | |||||
family history of Alzheimer’s disease | 0 | 8.3 | 87.3 | ||||
cigarettes per day measurement | 5 | 77.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | epoxide hydrolase 2 | VGNC:11967 | 464074 | |||||
Macaque | epoxide hydrolase 2 | 712926 | ||||||
Mouse | MGI:99500 | 13850 | ||||||
Rat | RGD:620732 | 65030 | ||||||
Dog | epoxide hydrolase 2 | VGNC:40416 | 477373 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | epoxide hydrolase 2 | |||||
Macaque | epoxide hydrolase 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | epoxide hydrolase 2 | |||||
PMID | Year | Title |
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