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Tbio
EPB41L5
Band 4.1-like protein 5

Protein Summary
Description
May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263713
  • ENSP00000263713
  • ENSG00000115109
  • ENST00000331393
  • ENSP00000329687
  • ENST00000443124
  • ENSP00000393722
  • ENST00000443902
  • ENSP00000393856
  • ENST00000452780
  • ENSP00000390439

Symbol
  • KIAA1548
  • YRT
  • BE37
  • YMO1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
1
transcription factor perturbation
0.99
interacting protein
0.96
biological process
0.92
histone modification site profile
0.89


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 55.01   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 128   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 55.01   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 128   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 26
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (103)
CHD9
Tbio
Family:  Epigenetic
Novelty:  0.06234268
p_int:  0.999998956
p_ni:  0.00000104
p_wrong:  4e-9
Score:  0.691
Data Source:  BioPlex,STRINGDB
UHRF1BP1
Tbio
Novelty:  0.1588079
p_int:  0.999998324
p_ni:  0.000001563
p_wrong:  1.14e-7
Data Source:  BioPlex
SETD1A
Tbio
Family:  Epigenetic
Novelty:  0.00248544
p_int:  0.99999381
p_ni:  0.00000619
Score:  0.612
Data Source:  BioPlex,STRINGDB
CXXC1
Tbio
Family:  Epigenetic
Novelty:  0.01019251
p_int:  0.999990085
p_ni:  0.000009915
Score:  0.54
Data Source:  BioPlex,STRINGDB
CWC22
Tbio
Novelty:  0.027689
p_int:  0.999888259
p_ni:  0.000111741
Score:  0.547
Data Source:  BioPlex,STRINGDB
NAF1
Tbio
Novelty:  2.99493689
p_int:  0.999841648
p_ni:  0.000158063
p_wrong:  2.88e-7
Score:  0.649
Data Source:  BioPlex,STRINGDB
EAF1
Tbio
Novelty:  0.81120425
p_int:  0.999822985
p_ni:  0.000177015
Data Source:  BioPlex
BOD1L1
Tdark
Novelty:  0.26485597
p_int:  0.999048744
p_ni:  0.000951256
Score:  0.664
Data Source:  BioPlex,STRINGDB
HECTD1
Tbio
Family:  Enzyme
Novelty:  0.28016112
p_int:  0.997826476
p_ni:  0.002173524
Score:  0.153
Data Source:  BioPlex,STRINGDB
PRICKLE3
Tbio
Novelty:  0.26347141
p_int:  0.997767949
p_ni:  0.002232051
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (5)
Neurexins and neuroligins (R-HSA-6794361)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Neurexins and neuroligins
Reactome
Neuronal System
Reactome
Protein-protein interactions at synapses
Name
Explore in Pharos
Explore in Source
Neurexins and neuroligins
Neuronal System
Protein-protein interactions at synapses
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (16)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
3
3
3
85.5
mean platelet volume
3
1
3
76.9
glomerular filtration rate
2
2
2
67.3
hemoglobin measurement
3
1
3
64.5
red blood cell density measurement
1
1
1
64.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
3
85.5
mean platelet volume
3
76.9
glomerular filtration rate
2
67.3
hemoglobin measurement
3
64.5
red blood cell density measurement
1
64.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
erythrocyte membrane protein band 4.1 like 5
700409
Mouse
MGI:103006
226352
Rat
RGD:1311366
304733
Dog
erythrocyte membrane protein band 4.1 like 5
VGNC:40398
403419
Horse
erythrocyte membrane protein band 4.1 like 5
VGNC:51453
100060271
Species
Name
OMA
EggNOG
Inparanoid
Macaque
erythrocyte membrane protein band 4.1 like 5
Mouse
Rat
Dog
erythrocyte membrane protein band 4.1 like 5
Horse
erythrocyte membrane protein band 4.1 like 5
Publication Statistics
PubMed Score 55.01
PubMed score by year
PubTator Score 11.10
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title