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Tdark
ENTHD1
ENTH domain-containing protein 1

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.19   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 86   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.19   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (65)
PLEKHH2
Tdark
Novelty:  0.24930341
p_int:  0.999999967
p_ni:  3.3e-8
Data Source:  BioPlex
NOS1AP
Tbio
Family:  Enzyme
Novelty:  0.0076555
p_int:  0.999999263
p_ni:  7.37e-7
Data Source:  BioPlex
LRRC45
Tdark
Novelty:  0.38407505
p_int:  0.999998209
p_ni:  0.000001072
p_wrong:  7.19e-7
Data Source:  BioPlex
C1orf226
Tdark
Novelty:  3.45031712
p_int:  0.999959959
p_ni:  0.000040041
Data Source:  BioPlex
TXLNG
Tbio
Novelty:  0.08274423
p_int:  0.999905163
p_ni:  0.000094837
Data Source:  BioPlex
ZMYM6
Tdark
Novelty:  0.4933879
p_int:  0.999757793
p_ni:  0.000242207
Data Source:  BioPlex
UACA
Tbio
Novelty:  0.05853699
p_int:  0.999434951
p_ni:  0.000565049
Data Source:  BioPlex
SASS6
Tbio
Novelty:  0.00680548
p_int:  0.99929786
p_ni:  0.000702125
p_wrong:  1.4e-8
Data Source:  BioPlex
SMTNL2
Tdark
Novelty:  0.33805653
p_int:  0.999221549
p_ni:  0.000777649
p_wrong:  8.02e-7
Data Source:  BioPlex
CEP55
Tbio
Novelty:  0.01328073
p_int:  0.998887413
p_ni:  0.001112241
p_wrong:  3.46e-7
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
1
1
59.8
1
1
1
54.4
eosinophil percentage of leukocytes
1
1
1
6.6
1
1
0
1.1
4.6
1
1
0
1.1
3.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
59.8
1
54.4
eosinophil percentage of leukocytes
1
6.6
0
1.1
4.6
0
1.1
3.1
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ENTH domain containing 1
VGNC:5258
744609
Macaque
ENTH domain containing 1
704302
Mouse
MGI:2686088
383075
Rat
RGD:1587874
685900
Dog
ENTH domain containing 1
VGNC:40380
481242
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ENTH domain containing 1
Macaque
ENTH domain containing 1
Mouse
Rat
Dog
ENTH domain containing 1
Publication Statistics
PubMed Score 0.19
PubMed score by year
PubTator Score 0.13
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title