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Tbio
GPRIN3
G protein-regulated inducer of neurite outgrowth 3

Protein Summary
Description
May be involved in neurite outgrowth.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000333209
  • ENSP00000328672
  • ENSG00000185477
  • ENST00000609438
  • ENSP00000476603

Symbol
  • KIAA2027
  • GRIN3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.61
microRNA
0.56
virus perturbation
0.5
cell line
0.49
histone modification site profile
0.47


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.26   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.26   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
1
2
77.6
body height
1
1
1
58.9
monocyte count
1
1
1
40.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
77.6
body height
1
58.9
monocyte count
1
40.7
Protein-Protein Interactions (30)
1 – 10 of 30
NLN
Tbio
Family: Enzyme
Novelty: 0.01217367
p_int: 0.995951872
p_ni: 0.004048128
p_wrong: 1e-9
Data Source: BioPlex
WIZ
Tbio
Family: TF
Novelty: 0.04458547
Score: 0.754
Data Source: STRINGDB
ZNF644
Tbio
Family: TF
Novelty: 0.12816167
Score: 0.725
Data Source: STRINGDB
GNAZ
Tbio
Novelty: 0.02008523
Score: 0.64
Data Source: STRINGDB
MMRN1
Tbio
Novelty: 0.03378128
Score: 0.557
Data Source: STRINGDB
TIGD2
Tdark
Novelty: 0.52702904
Score: 0.556
Data Source: STRINGDB
GNAO1
Tbio
Novelty: 0.00315097
Score: 0.529
Data Source: STRINGDB
SH2D5
Tdark
Novelty: 0.64067736
Score: 0.52
Data Source: STRINGDB
MAP6
Tbio
Novelty: 0.01266106
Score: 0.518
Data Source: STRINGDB
GRM2
Tchem
Family: GPCR
Novelty: 0.00132156
Score: 0.485
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.26

PubMed score by year
PubTator Score  0.82

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer