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Tbio
CTAG1A
Cancer/testis antigen 1

Protein Summary
Description
The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence. [provided by RefSeq, Jan 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000328435
  • ENSP00000332602
  • ENSG00000184033
  • ENST00000359887
  • ENSP00000352953
  • ENST00000599837
  • ENSP00000469441
  • ENSG00000268651

Symbol
  • CTAG
  • CTAG1
  • ESO1
  • LAGE2
  • LAGE2A
  • CTAG
  • ESO1
  • CT6.1
  • CTAG1
  • LAGE-2
  • LAGE2B
  • NY-ESO-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease
0.38
gene perturbation
0.36
biological term
0.33
interacting protein
0.31
small molecule perturbation
0.24


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 612.68   (req: < 5)
Gene RIFs: 83   (req: <= 3)
Antibodies: 681   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 612.68   (req: >= 5)
Gene RIFs: 83   (req: > 3)
Antibodies: 681   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (14 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-P78358-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 5 of 14
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
LIFEdb
Protein-Protein Interactions (135)
1 – 10 of 135
UBA52
Tbio
Novelty: 0.01637744
p_int: 0.9999996
p_ni: 4e-7
Data Source: BioPlex
GMIP
Tbio
Novelty: 0.06529054
p_int: 0.999994965
p_ni: 0.000005035
Data Source: BioPlex
FLCN
Tbio
Novelty: 0.0022007
p_int: 0.99859578
p_ni: 0.000995135
p_wrong: 0.000409086
Data Source: BioPlex
DDX19B
Tbio
Family: Enzyme
Novelty: 0.0504568
p_int: 0.928225642
p_ni: 0.071774358
Data Source: BioPlex
DPYSL4
Tbio
Family: Enzyme
Novelty: 0.0449179
p_int: 0.913258427
p_ni: 0.086696746
p_wrong: 0.000044827
Data Source: BioPlex
SEC23IP
Tbio
Novelty: 0.0925721
p_int: 0.880944008
p_ni: 0.119053661
p_wrong: 0.000002331
Data Source: BioPlex
PASK
Tbio
Family: Kinase
Novelty: 0.14004084
p_int: 0.875549104
p_ni: 0.124450896
Data Source: BioPlex
MAGEA3
Tbio
Novelty: 0.00285779
Score: 0.873
Data Source: STRINGDB
MAGEA1
Tbio
Novelty: 0.00506874
Score: 0.865
Data Source: STRINGDB
MAGEA4
Tbio
Novelty: 0.00949096
Score: 0.854
Data Source: STRINGDB
Publication Statistics
PubMed Score  612.68

PubMed score by year
PubTator Score  50.14

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer