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Tdark
LUZP6
Leucine zipper protein 6

Protein Summary
Description
A bi-cistronic transcript encodes the products of both the myotrophin and leucine zipper protein 6 genes, which are located on chromosome 7. A cryptic ORF at the 3' end of the myotrophin transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000589735
  • ENSP00000468007
  • ENSG00000267697

Symbol
  • MPD6
  • MPD6
  • MTPNUT
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.8
cellular component
0.64
pathway
0.52
cell line
0.45
tissue
0.45


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.03   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 8   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.03   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 8   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q538Z0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (5)
1 – 5 of 5
MTPN
Tbio
Novelty: 0.01070229
Score: 0.714
Data Source: STRINGDB
PIGY
Tbio
Family: Enzyme
Novelty: 0.17988252
Score: 0.583
Data Source: STRINGDB
PYURF
Tdark
Novelty: 0.19841169
Score: 0.441
Data Source: STRINGDB
CREB5
Tbio
Family: TF
Novelty: 0.03857106
Score: 0.422
Data Source: STRINGDB
SUB1
Tbio
Family: TF
Novelty: 0.00355509
Score: 0.422
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.03

PubMed score by year
PubTator Score  1.13

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer