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Tbio
RTL1
Retrotransposon-like protein 1

Protein Summary
Description
Plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta. This gene is a retrotransposon-derived, paternally expressed imprinted gene that is highly expressed at the late fetal stage in both the fetus and placenta. It has an overlapping maternally expressed antisense transcript, which contains several microRNAs targeting the transcripts of this gene through an RNA interference (RNAi) mechanism. This gene is essential for maintenance of the fetal capillaries. [provided by RefSeq, Jul 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000534062
  • ENSP00000435342
  • ENSG00000254656
  • ENST00000649591
  • ENSP00000497482

Symbol
  • MAR1
  • MART1
  • PEG11
  • HUR1
  • Mar1
  • MART1
  • PEG11
  • SIRH2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.59
cell line
0.58
PubMedID
0.51
tissue
0.48
protein complex
0.4


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.08   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.08   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
retrotransposon Gag like 1
718079
Mouse
MGI:2656842
353326
Rat
Dog
retrotransposon Gag like 1
VGNC:45791
100856720
Cow
retrotransposon Gag like 1
VGNC:34199
606737
Species
Name
OMA
EggNOG
Inparanoid
Macaque
retrotransposon Gag like 1
Mouse
Rat
Dog
retrotransposon Gag like 1
Cow
retrotransposon Gag like 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A6NKG5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (39)
1 – 10 of 39
DLK1
Tchem
Novelty: 0.00212394
Score: 0.833
Data Source: STRINGDB
DIO3
Tbio
Family: Enzyme
Novelty: 0.0047888
Score: 0.829
Data Source: STRINGDB
UROD
Tbio
Family: Enzyme
Novelty: 0.00337791
Score: 0.717
Data Source: STRINGDB
GOLGB1
Tbio
Novelty: 0.00943584
Score: 0.629
Data Source: STRINGDB
COPG2
Tbio
Novelty: 0.06126837
Score: 0.612
Data Source: STRINGDB
BEGAIN
Tbio
Family: Enzyme
Novelty: 0.18303898
Score: 0.607
Data Source: STRINGDB
AHNAK
Tbio
Novelty: 0.01201996
Score: 0.594
Data Source: STRINGDB
TAL1
Tbio
Family: TF
Novelty: 0.00294416
Score: 0.577
Data Source: STRINGDB
LMO7
Tbio
Novelty: 0.03508141
Score: 0.569
Data Source: STRINGDB
LHFPL6
Tbio
Novelty: 0.11121552
Score: 0.566
Data Source: STRINGDB
Publication Statistics
PubMed Score  56.08

PubMed score by year
PubTator Score  227.66

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer