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Tbio
TDRP
Testis development-related protein

Protein Summary
Description
Contributes to normal sperm motility, but not essential for male fertility.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000324079
  • ENSP00000315111
  • ENSG00000180190
  • ENST00000427263
  • ENSP00000408126
  • ENST00000523656
  • ENSP00000430325
  • ENST00000613071
  • ENSP00000479558

Symbol
  • C8orf42
  • Inm01
  • TDRP1
  • TDRP2
  • C8orf42
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.78
PubMedID
0.62
tissue sample
0.62
trait
0.61
transcription factor perturbation
0.47


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.46   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 45   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.46   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 45   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
prostate carcinoma
1
1
0
4.8
6.2
Hematochezia
1
1
0
4.8
6.2
response to radiation
1
1
0
4.8
6.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
prostate carcinoma
0
4.8
6.2
Hematochezia
0
4.8
6.2
response to radiation
0
4.8
6.2
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
testis development related protein
VGNC:786
463957
Mouse
MGI:1919398
72148
Rat
RGD:1559733
498662
Dog
testis development related protein
VGNC:49845
609462
Horse
testis development related protein [Source:HGNC Symbol;Acc:HGNC:26951]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
testis development related protein
Mouse
Rat
Dog
testis development related protein
Horse
testis development related protein [Source:HGNC Symbol;Acc:HGNC:26951]
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q86YL5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (5)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
UniProtKB
Protein-Protein Interactions (22)
1 – 10 of 22
ZNF596
Tdark
Family: TF
Novelty: 1.45268304
Score: 0.703
Data Source: STRINGDB
GPCPD1
Tdark
Family: Enzyme
Novelty: 0.03548168
Score: 0.676
Data Source: STRINGDB
ERICH1
Tdark
Novelty: 1.30496362
Score: 0.66
Data Source: STRINGDB
NMI
Tbio
Novelty: 0.06987427
Score: 0.659
Data Source: STRINGDB
CSDE1
Tbio
Family: TF
Novelty: 0.02625299
Score: 0.651
Data Source: STRINGDB
FBXO25
Tbio
Novelty: 0.1205608
Score: 0.65
Data Source: STRINGDB
SMCO2
Tdark
Novelty: 0.28394899
Score: 0.571
Data Source: STRINGDB
CAP2
Tbio
Family: Enzyme
Novelty: 0.1142507
Score: 0.51
Data Source: STRINGDB
RIOK1
Tchem
Family: Kinase
Novelty: 0.02476698
Score: 0.478
Data Source: STRINGDB
IGF2BP2
Tbio
Novelty: 0.0105554
Score: 0.471
Data Source: STRINGDB
Publication Statistics
PubMed Score  8.46

PubMed score by year
PubTator Score  2.87

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer