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Tdark
CR1L
Complement component receptor 1-like protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000508064
  • ENSP00000421736
  • ENSG00000197721
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.93
histone modification site profile
0.77
cell line
0.67
kinase perturbation
0.66
trait
0.61


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.12   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 37   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.12   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 37   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood sedimentation
1
1
1
51.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood sedimentation
1
51.4
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
complement C3b/C4b receptor 1 like
450119
Opossum
complement receptor type 1-like
100020467
Chicken
complement C3b/C4b receptor 1 like
CGNC:51109
419853
Species
Name
OMA
EggNOG
Inparanoid
Chimp
complement C3b/C4b receptor 1 like
Opossum
complement receptor type 1-like
Chicken
complement C3b/C4b receptor 1 like
Gene Ontology Terms (4)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
MGI
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (11)
1 – 10 of 11
C4A
Tbio
Novelty: 0.00062793
Score: 0.63
Data Source: STRINGDB
C4B
Tbio
Novelty: 0.00068357
Score: 0.629
Data Source: STRINGDB
DDHD1
Tbio
Family: Enzyme
Novelty: 0.05209502
Score: 0.524
Data Source: STRINGDB
C8G
Tbio
Novelty: 0.02322575
Score: 0.448
Data Source: STRINGDB
CD6
Tbio
Novelty: 0.00309541
Score: 0.442
Data Source: STRINGDB
EFCC1
Tdark
Novelty: 0.39794649
Score: 0.44
Data Source: STRINGDB
FHOD1
Tbio
Novelty: 0.02593459
Score: 0.426
Data Source: STRINGDB
TMEM120A
Tdark
Novelty: 0.21664358
Score: 0.418
Data Source: STRINGDB
SH2D4B
Tdark
Novelty: 1.34545865
Score: 0.414
Data Source: STRINGDB
TCP11L2
Tdark
Novelty: 1.78903335
Score: 0.411
Data Source: STRINGDB
Publication Statistics
PubMed Score  6.12

PubMed score by year
PubTator Score  2.26

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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