You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ZNF181
Zinc finger protein 181

Protein Summary
Description
May be involved in transcriptional regulation. Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.[supplied by OMIM, Jul 2003]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000459757
  • ENSP00000419435
  • ENSG00000197841
  • ENST00000492450
  • ENSP00000420727

Symbol
  • HHZ181
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.76
virus perturbation
0.64
tissue sample
0.61
protein domain
0.58
cell line
0.56


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.99   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 49   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.99   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 49   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 181
455943
Macaque
zinc finger protein 181 [Source:HGNC Symbol;Acc:HGNC:12971]
Dog
zinc finger protein 181
484590
Horse
zinc finger protein 181
100057907
Cow
zinc finger protein 181
767826
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 181
Macaque
zinc finger protein 181 [Source:HGNC Symbol;Acc:HGNC:12971]
Dog
zinc finger protein 181
Horse
zinc finger protein 181
Cow
zinc finger protein 181
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q2M3W8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (12)
1 – 10 of 12
ZZZ3
Tdark
Family: TF
Novelty: 0.23862921
Score: 0.611
Data Source: STRINGDB
ZMAT5
Tdark
Novelty: 0.97115324
Score: 0.575
Data Source: STRINGDB
ZNF608
Tdark
Novelty: 0.18575706
Score: 0.56
Data Source: STRINGDB
SCGB2B2
Tdark
Novelty: 0.80383495
Score: 0.477
Data Source: STRINGDB
MORF4L2
Tbio
Novelty: 0.09897629
Score: 0.468
Data Source: STRINGDB
ERLEC1
Tbio
Novelty: 0.01243855
Score: 0.457
Data Source: STRINGDB
LSM14A
Tbio
Novelty: 0.04728617
Score: 0.443
Data Source: STRINGDB
GABPB1
Tbio
Novelty: 0.01518726
Score: 0.435
Data Source: STRINGDB
ZDHHC11
Tdark
Family: Enzyme
Novelty: 0.35249931
Score: 0.435
Data Source: STRINGDB
UBA2
Tbio
Novelty: 0.01582807
Score: 0.431
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.99

PubMed score by year
PubTator Score  0.67

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer